NBP1-87855
antibody from Novus Biologicals
Targeting: KDM4A
JHDM3A, JMJD2, JMJD2A, KIAA0677, TDRD14A
Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [5]
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Validation data
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- Product number
- NBP1-87855 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-87855, RRID:AB_11007670
- Product name
- Rabbit Polyclonal Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references FBXO22 protein is required for optimal synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine.
A new isoform of the histone demethylase JMJD2A/KDM4A is required for skeletal muscle differentiation.
Dikopoltsev E, Foltyn VN, Zehl M, Jensen ON, Mori H, Radzishevsky I, Wolosker H
The Journal of biological chemistry 2014 Dec 5;289(49):33904-15
The Journal of biological chemistry 2014 Dec 5;289(49):33904-15
A new isoform of the histone demethylase JMJD2A/KDM4A is required for skeletal muscle differentiation.
Verrier L, Escaffit F, Chailleux C, Trouche D, Vandromme M
PLoS genetics 2011 Jun;7(6):e1001390
PLoS genetics 2011 Jun;7(6):e1001390
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Antibody [NBP1-87855] - Analysis in human cell line HEK 293.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Antibody [NBP1-87855] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Antibody [NBP1-87855] - Staining of human cerebellum shows strong positivity in nucleoli in Purkinje cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Antibody [NBP1-87855] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Antibody [NBP1-87855] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Antibody [NBP1-87855] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.