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- Antigen structure
- References [24]
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- Western blot [1]
- Immunoprecipitation [1]
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- Product number
- 17710-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17710-1-AP, RRID:AB_2282012
- Product name
- MPP5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MPP5 antibody (Cat. #17710-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Human CRB1 and CRB2 form homo- and heteromeric protein complexes in the retina.
ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.
PATJ inhibits histone deacetylase 7 to control tight junction formation and cell polarity.
Pals1 functions in redundancy with SMAP1 to inhibit Arf6 in order to prevent Rac1-dependent colorectal cancer cell migration and invasion.
Multicellular rosettes link mesenchymal-epithelial transition to radial intercalation in the mouse axial mesoderm.
An entosis-like process induces mitotic disruption in Pals1 microcephaly pathogenesis.
RAB6 and dynein drive post-Golgi apical transport to prevent neuronal progenitor delamination.
The evolutionary history of the polyQ tract in huntingtin sheds light on its functional pro-neural activities.
Crumbs2 Is an Essential Slit Diaphragm Protein of the Renal Filtration Barrier.
CD13 orients the apical-basal polarity axis necessary for lumen formation.
Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation.
Choroid plexus epithelial cells express the adhesion protein P-cadherin at cell-cell contacts and syntaxin-4 in the luminal membrane domain.
BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment.
Mosaic Analysis with Double Markers Reveals Distinct Sequential Functions of Lgl1 in Neural Stem Cells.
Applying a new quantitative global breast MRI feature analysis scheme to assess tumor response to chemotherapy.
Microcephaly Proteins Wdr62 and Aspm Define a Mother Centriole Complex Regulating Centriole Biogenesis, Apical Complex, and Cell Fate.
Crumbs 2 prevents cortical abnormalities in mouse dorsal telencephalon.
Targeted ablation of CRB1 and CRB2 in retinal progenitor cells mimics Leber congenital amaurosis.
Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background.
MPP3 regulates levels of PALS1 and adhesion between photoreceptors and Müller cells.
MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex.
Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene.
Atp6ap2/(pro)renin receptor interacts with Par3 as a cell polarity determinant required for laminar formation during retinal development in mice.
PALS1 is essential for retinal pigment epithelium structure and neural retina stratification.
Stehle IF, Imventarza JA, Woerz F, Hoffmann F, Boldt K, Beyer T, Quinn PM, Ueffing M
Life science alliance 2024 Jun;7(6)
Life science alliance 2024 Jun;7(6)
ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.
Pearson GJ, Mears HV, Broncel M, Snijders AP, Bauer DLV, Carlton JG
Science advances 2024 Apr 5;10(14):eadl5012
Science advances 2024 Apr 5;10(14):eadl5012
PATJ inhibits histone deacetylase 7 to control tight junction formation and cell polarity.
Fiedler J, Moennig T, Hinrichs JH, Weber A, Wagner T, Hemmer T, Schröter R, Weide T, Epting D, Bergmann C, Nedvetsky P, Krahn MP
Cellular and molecular life sciences : CMLS 2023 Oct 25;80(11):333
Cellular and molecular life sciences : CMLS 2023 Oct 25;80(11):333
Pals1 functions in redundancy with SMAP1 to inhibit Arf6 in order to prevent Rac1-dependent colorectal cancer cell migration and invasion.
Harms J, Lüttgenau SM, Emming C, Guske J, Weber K, Wagner T, Schowe L, Nedvetsky P, Krahn MP
Cancer gene therapy 2023 Mar;30(3):497-506
Cancer gene therapy 2023 Mar;30(3):497-506
Multicellular rosettes link mesenchymal-epithelial transition to radial intercalation in the mouse axial mesoderm.
Gredler ML, Zallen JA
Developmental cell 2023 Jun 5;58(11):933-950.e5
Developmental cell 2023 Jun 5;58(11):933-950.e5
An entosis-like process induces mitotic disruption in Pals1 microcephaly pathogenesis.
Sterling NA, Park JY, Park R, Cho SH, Kim S
Nature communications 2023 Jan 5;14(1):82
Nature communications 2023 Jan 5;14(1):82
RAB6 and dynein drive post-Golgi apical transport to prevent neuronal progenitor delamination.
Brault JB, Bardin S, Lampic M, Carpentieri JA, Coquand L, Penisson M, Lachuer H, Victoria GS, Baloul S, El Marjou F, Boncompain G, Miserey-Lenkei S, Belvindrah R, Fraisier V, Francis F, Perez F, Goud B, Baffet AD
EMBO reports 2022 Oct 6;23(10):e54605
EMBO reports 2022 Oct 6;23(10):e54605
The evolutionary history of the polyQ tract in huntingtin sheds light on its functional pro-neural activities.
Iennaco R, Formenti G, Trovesi C, Rossi RL, Zuccato C, Lischetti T, Bocchi VD, Scolz A, Martínez-Labarga C, Rickards O, Pacifico M, Crottini A, Møller AP, Chen RZ, Vogt TF, Pavesi G, Horner DS, Saino N, Cattaneo E
Cell death and differentiation 2022 Feb;29(2):293-305
Cell death and differentiation 2022 Feb;29(2):293-305
Crumbs2 Is an Essential Slit Diaphragm Protein of the Renal Filtration Barrier.
Möller-Kerutt A, Rodriguez-Gatica JE, Wacker K, Bhatia R, Siebrasse JP, Boon N, Van Marck V, Boor P, Kubitscheck U, Wijnholds J, Pavenstädt H, Weide T
Journal of the American Society of Nephrology : JASN 2021 May 3;32(5):1053-1070
Journal of the American Society of Nephrology : JASN 2021 May 3;32(5):1053-1070
CD13 orients the apical-basal polarity axis necessary for lumen formation.
Wang LT, Rajah A, Brown CM, McCaffrey L
Nature communications 2021 Aug 4;12(1):4697
Nature communications 2021 Aug 4;12(1):4697
Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation.
Hughes LJ, Park R, Lee MJ, Terry BK, Lee DJ, Kim H, Cho SH, Kim S
Developmental biology 2020 Jan 1;457(1):150-162
Developmental biology 2020 Jan 1;457(1):150-162
Choroid plexus epithelial cells express the adhesion protein P-cadherin at cell-cell contacts and syntaxin-4 in the luminal membrane domain.
Christensen IB, Mogensen EN, Damkier HH, Praetorius J
American journal of physiology. Cell physiology 2018 May 1;314(5):C519-C533
American journal of physiology. Cell physiology 2018 May 1;314(5):C519-C533
BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment.
Hsu Y, Garrison JE, Kim G, Schmitz AR, Searby CC, Zhang Q, Datta P, Nishimura DY, Seo S, Sheffield VC
PLoS genetics 2017 Oct;13(10):e1007057
PLoS genetics 2017 Oct;13(10):e1007057
Mosaic Analysis with Double Markers Reveals Distinct Sequential Functions of Lgl1 in Neural Stem Cells.
Beattie R, Postiglione MP, Burnett LE, Laukoter S, Streicher C, Pauler FM, Xiao G, Klezovitch O, Vasioukhin V, Ghashghaei TH, Hippenmeyer S
Neuron 2017 May 3;94(3):517-533.e3
Neuron 2017 May 3;94(3):517-533.e3
Applying a new quantitative global breast MRI feature analysis scheme to assess tumor response to chemotherapy.
Aghaei F, Tan M, Hollingsworth AB, Zheng B
Journal of magnetic resonance imaging : JMRI 2016 Nov;44(5):1099-1106
Journal of magnetic resonance imaging : JMRI 2016 Nov;44(5):1099-1106
Microcephaly Proteins Wdr62 and Aspm Define a Mother Centriole Complex Regulating Centriole Biogenesis, Apical Complex, and Cell Fate.
Jayaraman D, Kodani A, Gonzalez DM, Mancias JD, Mochida GH, Vagnoni C, Johnson J, Krogan N, Harper JW, Reiter JF, Yu TW, Bae BI, Walsh CA
Neuron 2016 Nov 23;92(4):813-828
Neuron 2016 Nov 23;92(4):813-828
Crumbs 2 prevents cortical abnormalities in mouse dorsal telencephalon.
Dudok JJ, Murtaza M, Henrique Alves C, Rashbass P, Wijnholds J
Neuroscience research 2016 Jul;108:12-23
Neuroscience research 2016 Jul;108:12-23
Targeted ablation of CRB1 and CRB2 in retinal progenitor cells mimics Leber congenital amaurosis.
Pellissier LP, Alves CH, Quinn PM, Vos RM, Tanimoto N, Lundvig DM, Dudok JJ, Hooibrink B, Richard F, Beck SC, Huber G, Sothilingam V, Garcia Garrido M, Le Bivic A, Seeliger MW, Wijnholds J
PLoS genetics 2013;9(12):e1003976
PLoS genetics 2013;9(12):e1003976
Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background.
Alves CH, Bossers K, Vos RM, Essing AH, Swagemakers S, van der Spek PJ, Verhaagen J, Wijnholds J
PloS one 2013;8(12):e82532
PloS one 2013;8(12):e82532
MPP3 regulates levels of PALS1 and adhesion between photoreceptors and Müller cells.
Dudok JJ, Sanz AS, Lundvig DM, Sothilingam V, Garcia Garrido M, Klooster J, Seeliger MW, Wijnholds J
Glia 2013 Oct;61(10):1629-44
Glia 2013 Oct;61(10):1629-44
MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex.
Dudok JJ, Sanz AS, Lundvig DM, Wijnholds J
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 May 8;33(19):8518-27
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 May 8;33(19):8518-27
Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene.
Alves CH, Sanz AS, Park B, Pellissier LP, Tanimoto N, Beck SC, Huber G, Murtaza M, Richard F, Sridevi Gurubaran I, Garcia Garrido M, Levelt CN, Rashbass P, Le Bivic A, Seeliger MW, Wijnholds J
Human molecular genetics 2013 Jan 1;22(1):35-50
Human molecular genetics 2013 Jan 1;22(1):35-50
Atp6ap2/(pro)renin receptor interacts with Par3 as a cell polarity determinant required for laminar formation during retinal development in mice.
Kanda A, Noda K, Yuki K, Ozawa Y, Furukawa T, Ichihara A, Ishida S
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Dec 4;33(49):19341-51
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Dec 4;33(49):19341-51
PALS1 is essential for retinal pigment epithelium structure and neural retina stratification.
Park B, Alves CH, Lundvig DM, Tanimoto N, Beck SC, Huber G, Richard F, Klooster J, Andlauer TF, Swindell EC, Jamrich M, Le Bivic A, Seeliger MW, Wijnholds J
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Nov 23;31(47):17230-41
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Nov 23;31(47):17230-41
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Y79 cells were subjected to SDS PAGE followed by western blot with 17710-1-AP(MPP5 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MPP5 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MPP5. This antibody recognizes human,mouse,rat antigen. The MPP5 antibody has been validated for the following applications: ELISA, WB, IP analysis.
