Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 13966-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13966-1-AP, RRID:AB_2189776
- Product name
- ZnT7 antibody
- Antibody type
- Polyclonal
- Description
- ZnT7 antibody (Cat. #13966-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The organic zinc with moderate chelation strength enhances the expression of related transporters in the jejunum and ileum of broilers.
Organic zinc with moderate chelation strength enhances zinc absorption in the small intestine and expression of related transporters in the duodenum of broilers.
ZNT7 binds to CD40 and influences CD154-triggered p38 MAPK activity in B lymphocytes-a possible regulatory mechanism for zinc in immune function.
Zinc deficiency mediates alcohol-induced apoptotic cell death in the liver of rats through activating ER and mitochondrial cell death pathways.
Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis.
Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder.
Dysregulation of hepatic zinc transporters in a mouse model of alcoholic liver disease.
Deregulation of biometal homeostasis: the missing link for neuronal ceroid lipofuscinoses?
Altered biometal homeostasis is associated with CLN6 mRNA loss in mouse neuronal ceroid lipofuscinosis.
Hu Y, Huang Y, Wang C, Zhang W, Qu Y, Li D, Wu W, Gao F, Zhu L, Wu B, Zhang L, Cui X, Li T, Geng Y, Liao X, Luo X
Poultry science 2023 Mar;102(3):102477
Poultry science 2023 Mar;102(3):102477
Organic zinc with moderate chelation strength enhances zinc absorption in the small intestine and expression of related transporters in the duodenum of broilers.
Hu Y, Wang C, Wu W, Qu Y, Zhang W, Li D, Zhu L, Gao F, Wu B, Zhang L, Cui X, Li T, Geng Y, Luo X
Frontiers in physiology 2022;13:952941
Frontiers in physiology 2022;13:952941
ZNT7 binds to CD40 and influences CD154-triggered p38 MAPK activity in B lymphocytes-a possible regulatory mechanism for zinc in immune function.
Tepaamorndech S, Oort P, Kirschke CP, Cai Y, Huang L
FEBS open bio 2017 May;7(5):675-690
FEBS open bio 2017 May;7(5):675-690
Zinc deficiency mediates alcohol-induced apoptotic cell death in the liver of rats through activating ER and mitochondrial cell death pathways.
Sun Q, Zhong W, Zhang W, Li Q, Sun X, Tan X, Sun X, Dong D, Zhou Z
American journal of physiology. Gastrointestinal and liver physiology 2015 May 1;308(9):G757-66
American journal of physiology. Gastrointestinal and liver physiology 2015 May 1;308(9):G757-66
Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis.
Kaneko M, Noguchi T, Ikegami S, Sakurai T, Kakita A, Toyoshima Y, Kambe T, Yamada M, Inden M, Hara H, Oyanagi K, Inuzuka T, Takahashi H, Hozumi I
Journal of neuroscience research 2015 Feb;93(2):370-9
Journal of neuroscience research 2015 Feb;93(2):370-9
Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder.
Grubman A, Lidgerwood GE, Duncan C, Bica L, Tan JL, Parker SJ, Caragounis A, Meyerowitz J, Volitakis I, Moujalled D, Liddell JR, Hickey JL, Horne M, Longmuir S, Koistinaho J, Donnelly PS, Crouch PJ, Tammen I, White AR, Kanninen KM
Acta neuropathologica communications 2014 Feb 28;2:25
Acta neuropathologica communications 2014 Feb 28;2:25
Dysregulation of hepatic zinc transporters in a mouse model of alcoholic liver disease.
Sun Q, Li Q, Zhong W, Zhang J, Sun X, Tan X, Yin X, Sun X, Zhang X, Zhou Z
American journal of physiology. Gastrointestinal and liver physiology 2014 Aug 1;307(3):G313-22
American journal of physiology. Gastrointestinal and liver physiology 2014 Aug 1;307(3):G313-22
Deregulation of biometal homeostasis: the missing link for neuronal ceroid lipofuscinoses?
Grubman A, Pollari E, Duncan C, Caragounis A, Blom T, Volitakis I, Wong A, Cooper J, Crouch PJ, Koistinaho J, Jalanko A, White AR, Kanninen KM
Metallomics : integrated biometal science 2014 Apr;6(4):932-43
Metallomics : integrated biometal science 2014 Apr;6(4):932-43
Altered biometal homeostasis is associated with CLN6 mRNA loss in mouse neuronal ceroid lipofuscinosis.
Kanninen KM, Grubman A, Caragounis A, Duncan C, Parker SJ, Lidgerwood GE, Volitakis I, Ganio G, Crouch PJ, White AR
Biology open 2013 Jun 15;2(6):635-46
Biology open 2013 Jun 15;2(6):635-46
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse lung tissue were subjected to SDS PAGE followed by western blot with 13966-1-AP(SLC30A7 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of A431 cells, using SLC30A7 antibody 13966-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line