16099-1-AP

antibody from Proteintech Group

Targeting: BBOX1 BBH, BBOX, G-BBH, gamma-BBH

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

16099-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#16099-1-AP, RRID:AB_2243498

Product name

BBOX1 antibody

Antibody type

Polyclonal

Description

BBOX1 antibody (Cat. #16099-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

The E3 ubiquitin ligase TRIM31 enhances the progression of esophageal cancer through the ubiquitination of BBOX1.

Ge L, Sun M, Xu D, Sun G
Cellular signalling 2025 Nov;135:111975

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GSTK1 suppresses HCC aggravation via L-carnitine metabolism by PGAM5/DRP1 complex-mediated mitochondrial quality control.

Shi Y, Zhang J, Song B, Zhang H, He J, Ding K, Wang F, Yu W, Zhangyuan G, Jin K, Zhang W, Sun B
Journal of experimental & clinical cancer research : CR 2025 Nov 24;45(1):1

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Conjugated Lithocholic Acid Activates Hepatic TGR5 to Promote Lipotoxicity and MASLD-MASH Transition by Disrupting Carnitine Biosynthesis.

Lian S, Lu M, Jiajing L, Zhang B, Fang Y, Wang X, Zheng M, Ni Y, Xu G, Yang Y, Jiang R
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2410602

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BBOX1 mediates metabolic reprogramming driven by hypoxia and participates in the malignant progress of high-grade serous ovarian cancer.

Huang J, Tang Y, Li Y, Wei W, Kang F, Tan S, Lin L, Lu X, Wei H, Wang N
Biochimica et biophysica acta. Molecular cell research 2024 Dec;1871(8):119830

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CRIP1 suppresses BBOX1-mediated carnitine metabolism to promote stemness in hepatocellular carcinoma.

Wang J, Zhou Y, Zhang D, Zhao W, Lu Y, Liu C, Lin W, Zhang Y, Chen K, Wang H, Zhao L
The EMBO journal 2022 Aug 1;41(15):e110218

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

human brain tissue were subjected to SDS PAGE followed by western blot with 16099-1-AP(BBOX1 antibody) at dilution of 1:800

Sample type

tissue

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of HepG2 cells, using BBOX1 antibody 16099-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

Sample type

cell line