BS7873

antibody from Bioworld Technology, Inc
Targeting: BBOX1 BBH, BBOX, G-BBH, gamma-BBH
Provider product page for BS7873

Antibody data

Product number
BS7873 - Provider product page
Provider
Bioworld Technology, Inc
Product name
BBOX1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human BBOX1.
Description
BBOX1 (butyrobetaine (ÎÛ), 2-oxoglutarate dioxygenase 1), also known as BBH, BBOX, G-BBH (ÎÛ-butyrobetaine hydroxylase) or ÎÛ-BBH, is a member of the ÎÛ-BBH/TMLD family of proteins. Localizing to the cytoplasm and predominantly expressed in kidney, BBOX1 plays a role in the biosynthesis of amines, polyamines and carnitines. More specifically, BBOX1 catalyzes the hydroxylation of ÎÛ-butyrobetaine to L-carnitine, a reaction that requires iron and ascorbate as cofactors. This is the last of five steps comprising the L-carnitine biosynthesis pathway and it is important for the proper transport of activated fatty acids across the mitochondrial membrane. Coupled to this reaction, BBOX1 simultaneously catalyzes the oxidative decarboxylation of Ï«-ketoglutarate to succinate.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
BBOX1 protein structure - BS7873 shown in red.