PTH2R

The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Description

parathyroid hormone 2 receptor

Protein family

FDA approved drug targets, G-protein coupled receptors, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted membrane proteins

Chromosome

2:q34 (208359714 - 208854503)

Ensembl ID

ENSG00000144407  (ver. 99.38)

Orthologs

Mouse Pth2r: ENSMUSG00000025946

UniProt

P49190

neXtProt

NX_P49190

Human splice variants
Mouse splice variants