Antibody data
- Antibody Data
- Antigen structure
- References [27]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10370-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10370-1-AP, RRID:AB_2297897
- Product name
- MOV10 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MOV10 antibody (Cat. #10370-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Optimized infrared photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (IR-PAR-CLIP) protocol identifies novel IGF2BP3-interacting RNAs in colon cancer cells.
ZCCHC3 is a stress granule zinc knuckle protein that strongly suppresses LINE-1 retrotransposition.
Atlas of interactions between SARS-CoV-2 macromolecules and host proteins.
Sequestration of LINE-1 in cytosolic aggregates by MOV10 restricts retrotransposition.
The solution structure of Dead End bound to AU-rich RNA reveals an unusual mode of tandem RRM-RNA recognition required for mRNA regulation.
A male germ-cell-specific ribosome controls male fertility.
Proximity-based labeling reveals DNA damage-induced phosphorylation of fused in sarcoma (FUS) causes distinct changes in the FUS protein interactome.
The association of MOV10 polymorphism and expression levels with preeclampsia in the Chinese Han population.
Multivalent Proteins Rapidly and Reversibly Phase-Separate upon Osmotic Cell Volume Change.
Host restriction of emerging high-pathogenic bunyaviruses via MOV10 by targeting viral nucleoprotein and blocking ribonucleoprotein assembly.
Biological and RNA regulatory function of MOV10 in mammalian germ cells.
MOV10 binding circ-DICER1 regulates the angiogenesis of glioma via miR-103a-3p/miR-382-5p mediated ZIC4 expression change.
MOV10 sequesters the RNP of influenza A virus in the cytoplasm and is antagonized by viral NS1 protein.
Stress granules and RNA processing bodies are novel autoantibody targets in systemic sclerosis.
ARF1 regulates adhesion of MDA-MB-231 invasive breast cancer cells through formation of focal adhesions.
The role of Moloney leukemia virus 10 in hepatitis B virus expression in hepatoma cells.
MOV10 Is a 5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs.
MOV10 RNA helicase is a potent inhibitor of retrotransposition in cells.
Moloney leukemia virus type 10 inhibits reverse transcription and retrotransposition of intracisternal a particles.
Endogenous MOV10 inhibits the retrotransposition of endogenous retroelements but not the replication of exogenous retroviruses.
Identification of molecular determinants from Moloney leukemia virus 10 homolog (MOV10) protein for virion packaging and anti-HIV-1 activity.
Moloney leukemia virus 10 (MOV10) protein inhibits retrovirus replication.
Perturbation of the P-body component Mov10 inhibits HIV-1 infectivity.
Combined proteomic-RNAi screen for host factors involved in human hepatitis delta virus replication.
A coordinated local translational control point at the synapse involving relief from silencing and MOV10 degradation.
Capped small RNAs and MOV10 in human hepatitis delta virus replication.
APOBEC3G and APOBEC3F require an endogenous cofactor to block HIV-1 replication.
Anisimova AS, Karagöz GE
RNA (New York, N.Y.) 2023 Nov;29(11):1818-1836
RNA (New York, N.Y.) 2023 Nov;29(11):1818-1836
ZCCHC3 is a stress granule zinc knuckle protein that strongly suppresses LINE-1 retrotransposition.
Goodier JL, Wan H, Soares AO, Sanchez L, Selser JM, Pereira GC, Karma S, García-Pérez JL, Kazazian HH Jr, García Cañadas MM
PLoS genetics 2023 Jul;19(7):e1010795
PLoS genetics 2023 Jul;19(7):e1010795
Atlas of interactions between SARS-CoV-2 macromolecules and host proteins.
Li G, Tang Z, Fan W, Wang X, Huang L, Jia Y, Wang M, Hu Z, Zhou Y
Cell insight 2023 Feb;2(1):100068
Cell insight 2023 Feb;2(1):100068
Sequestration of LINE-1 in cytosolic aggregates by MOV10 restricts retrotransposition.
Arora R, Bodak M, Penouty L, Hackman C, Ciaudo C
EMBO reports 2022 Sep 5;23(9):e54458
EMBO reports 2022 Sep 5;23(9):e54458
The solution structure of Dead End bound to AU-rich RNA reveals an unusual mode of tandem RRM-RNA recognition required for mRNA regulation.
Duszczyk MM, Wischnewski H, Kazeeva T, Arora R, Loughlin FE, von Schroetter C, Pradère U, Hall J, Ciaudo C, Allain FH
Nature communications 2022 Oct 6;13(1):5892
Nature communications 2022 Oct 6;13(1):5892
A male germ-cell-specific ribosome controls male fertility.
Li H, Huo Y, He X, Yao L, Zhang H, Cui Y, Xiao H, Xie W, Zhang D, Wang Y, Zhang S, Tu H, Cheng Y, Guo Y, Cao X, Zhu Y, Jiang T, Guo X, Qin Y, Sha J
Nature 2022 Dec;612(7941):725-731
Nature 2022 Dec;612(7941):725-731
Proximity-based labeling reveals DNA damage-induced phosphorylation of fused in sarcoma (FUS) causes distinct changes in the FUS protein interactome.
Johnson MA, Nuckols TA, Merino P, Bagchi P, Nandy S, Root J, Taylor G, Seyfried NT, Kukar T
The Journal of biological chemistry 2022 Aug;298(8):102135
The Journal of biological chemistry 2022 Aug;298(8):102135
The association of MOV10 polymorphism and expression levels with preeclampsia in the Chinese Han population.
Tang Q, Wang L, Cai R, Zhang L, Zhang X, Liu X, Liu S
Molecular genetics & genomic medicine 2021 Jan;9(1):e1564
Molecular genetics & genomic medicine 2021 Jan;9(1):e1564
Multivalent Proteins Rapidly and Reversibly Phase-Separate upon Osmotic Cell Volume Change.
Jalihal AP, Pitchiaya S, Xiao L, Bawa P, Jiang X, Bedi K, Parolia A, Cieslik M, Ljungman M, Chinnaiyan AM, Walter NG
Molecular cell 2020 Sep 17;79(6):978-990.e5
Molecular cell 2020 Sep 17;79(6):978-990.e5
Host restriction of emerging high-pathogenic bunyaviruses via MOV10 by targeting viral nucleoprotein and blocking ribonucleoprotein assembly.
Mo Q, Xu Z, Deng F, Wang H, Ning YJ
PLoS pathogens 2020 Dec;16(12):e1009129
PLoS pathogens 2020 Dec;16(12):e1009129
Biological and RNA regulatory function of MOV10 in mammalian germ cells.
Fu K, Tian S, Tan H, Wang C, Wang H, Wang M, Wang Y, Chen Z, Wang Y, Yue Q, Xu Q, Zhang S, Li H, Xie J, Lin M, Luo M, Chen F, Ye L, Zheng K
BMC biology 2019 May 14;17(1):39
BMC biology 2019 May 14;17(1):39
MOV10 binding circ-DICER1 regulates the angiogenesis of glioma via miR-103a-3p/miR-382-5p mediated ZIC4 expression change.
He Q, Zhao L, Liu X, Zheng J, Liu Y, Liu L, Ma J, Cai H, Li Z, Xue Y
Journal of experimental & clinical cancer research : CR 2019 Jan 8;38(1):9
Journal of experimental & clinical cancer research : CR 2019 Jan 8;38(1):9
MOV10 sequesters the RNP of influenza A virus in the cytoplasm and is antagonized by viral NS1 protein.
Li J, Hu S, Xu F, Mei S, Liu X, Yin L, Zhao F, Zhao X, Sun H, Xiong Z, Zhang D, Cen S, Wang J, Liang C, Guo F
The Biochemical journal 2019 Feb 5;476(3):467-481
The Biochemical journal 2019 Feb 5;476(3):467-481
Stress granules and RNA processing bodies are novel autoantibody targets in systemic sclerosis.
Johnson ME, Grassetti AV, Taroni JN, Lyons SM, Schweppe D, Gordon JK, Spiera RF, Lafyatis R, Anderson PJ, Gerber SA, Whitfield ML
Arthritis research & therapy 2016 Jan 22;18:27
Arthritis research & therapy 2016 Jan 22;18:27
ARF1 regulates adhesion of MDA-MB-231 invasive breast cancer cells through formation of focal adhesions.
Schlienger S, Ramirez RA, Claing A
Cellular signalling 2015 Mar;27(3):403-15
Cellular signalling 2015 Mar;27(3):403-15
The role of Moloney leukemia virus 10 in hepatitis B virus expression in hepatoma cells.
Ma YX, Li D, Fu LJ, Fu BQ, Chen SJ, Xu WZ, Teng X, Song ZW, Gu HX
Virus research 2015 Feb 2;197:85-91
Virus research 2015 Feb 2;197:85-91
MOV10 Is a 5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs.
Gregersen LH, Schueler M, Munschauer M, Mastrobuoni G, Chen W, Kempa S, Dieterich C, Landthaler M
Molecular cell 2014 May 22;54(4):573-85
Molecular cell 2014 May 22;54(4):573-85
MOV10 RNA helicase is a potent inhibitor of retrotransposition in cells.
Goodier JL, Cheung LE, Kazazian HH Jr
PLoS genetics 2012;8(10):e1002941
PLoS genetics 2012;8(10):e1002941
Moloney leukemia virus type 10 inhibits reverse transcription and retrotransposition of intracisternal a particles.
Lu C, Luo Z, Jäger S, Krogan NJ, Peterlin BM
Journal of virology 2012 Oct;86(19):10517-23
Journal of virology 2012 Oct;86(19):10517-23
Endogenous MOV10 inhibits the retrotransposition of endogenous retroelements but not the replication of exogenous retroviruses.
Arjan-Odedra S, Swanson CM, Sherer NM, Wolinsky SM, Malim MH
Retrovirology 2012 Jun 22;9:53
Retrovirology 2012 Jun 22;9:53
Identification of molecular determinants from Moloney leukemia virus 10 homolog (MOV10) protein for virion packaging and anti-HIV-1 activity.
Abudu A, Wang X, Dang Y, Zhou T, Xiang SH, Zheng YH
The Journal of biological chemistry 2012 Jan 6;287(2):1220-8
The Journal of biological chemistry 2012 Jan 6;287(2):1220-8
Moloney leukemia virus 10 (MOV10) protein inhibits retrovirus replication.
Wang X, Han Y, Dang Y, Fu W, Zhou T, Ptak RG, Zheng YH
The Journal of biological chemistry 2010 May 7;285(19):14346-55
The Journal of biological chemistry 2010 May 7;285(19):14346-55
Perturbation of the P-body component Mov10 inhibits HIV-1 infectivity.
Furtak V, Mulky A, Rawlings SA, Kozhaya L, Lee K, Kewalramani VN, Unutmaz D
PloS one 2010 Feb 5;5(2):e9081
PloS one 2010 Feb 5;5(2):e9081
Combined proteomic-RNAi screen for host factors involved in human hepatitis delta virus replication.
Cao D, Haussecker D, Huang Y, Kay MA
RNA (New York, N.Y.) 2009 Nov;15(11):1971-9
RNA (New York, N.Y.) 2009 Nov;15(11):1971-9
A coordinated local translational control point at the synapse involving relief from silencing and MOV10 degradation.
Banerjee S, Neveu P, Kosik KS
Neuron 2009 Dec 24;64(6):871-84
Neuron 2009 Dec 24;64(6):871-84
Capped small RNAs and MOV10 in human hepatitis delta virus replication.
Haussecker D, Cao D, Huang Y, Parameswaran P, Fire AZ, Kay MA
Nature structural & molecular biology 2008 Jul;15(7):714-21
Nature structural & molecular biology 2008 Jul;15(7):714-21
APOBEC3G and APOBEC3F require an endogenous cofactor to block HIV-1 replication.
Han Y, Wang X, Dang Y, Zheng YH
PLoS pathogens 2008 Jul 4;4(7):e1000095
PLoS pathogens 2008 Jul 4;4(7):e1000095
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 10370-1-AP(MOV10 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MOV10 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MOV10. This antibody recognizes human,mouse,rat antigen. The MOV10 antibody has been validated for the following applications: ELISA, WB, IHC, IP, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-MOV10 (IP:10370-1-AP, 3ug; Detection:10370-1-AP 1:800) with HepG2 cells lysate 1000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 10370-1-AP(MOV10 antibody) at dilution of 1:50 (under 25x lens)
- Sample type
- tissue