RA0527

antibody from Oursmab

Targeting: NGF NGFB

Western blot (Supportive data in Antibodypedia)

ELISA (Supportive data in Antibodypedia)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0527

Provider

Oursmab

Product name

Tanezumab (Biosimilar Reference Antibody) (NGFB)

Antibody type

Monoclonal

Description

Tanezumab is a humanized monoclonal antibody targeting nerve growth factor (NGF). It binds to NGF, inhibiting its interaction with tropomyosin receptor kinase A (TrkA) and p75 neurotrophin receptors, thereby reducing pain signaling. It was developed for the treatment of chronic pain conditions such as osteoarthritis, chronic low back pain, and cancer pain, though regulatory approval has been limited due to safety concerns.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

Western blot

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

Tanezumab (Biosimilar Reference Antibody) (NGFB)-RA0527-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.

ELISA

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

ELISA plate pre-coated Antigen protein, can bind Tanezumab (Biosimilar Reference Antibody) (NGFB)-RA0527 in a linear range of 3.91-125 ng/mL.