Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- ABIN1881138 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Calsequestrin 2 (Cardiac Muscle) (CASQ2) (Center), (AA 79-107) antibody
- Antibody type
- Polyclonal
- Antigen
- This CASQ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-107 amino acids from the Central region of human CASQ2.
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- Center,AA 79-107
- Antibody clone number
- RB41817
- Vial size
- 400 μL
- Concentration
- 0.5 mg/mL
Submitted references The human CASQ2 mutation K206N is associated with hyperglycosylation and altered cellular calcium handling.
Unique isoform-specific properties of calsequestrin in the heart and skeletal muscle.
Kirchhefer U, Wehrmeister D, Postma AV, Pohlentz G, Mormann M, Kucerova D, Müller FU, Schmitz W, Schulze-Bahr E, Wilde AA, Neumann J
Journal of molecular and cellular cardiology 2010 Jul;49(1):95-105
Journal of molecular and cellular cardiology 2010 Jul;49(1):95-105
Unique isoform-specific properties of calsequestrin in the heart and skeletal muscle.
Wei L, Hanna AD, Beard NA, Dulhunty AF
Cell calcium 2009 May;45(5):474-84
Cell calcium 2009 May;45(5):474-84
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- CASQ2 Antibody (Center) (ABIN1881138) western blot analysis in SK-BR-3 cell line lysates (35 μg/lane). This demonstrates the CASQ2 antibody detected the CASQ2 protein (arrow).