HPA008436

antibody from Atlas Antibodies

Targeting: HJURP DKFZp762E1312, FAKTS, hFLEG1, URLC9

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA008436

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA008436, RRID:AB_1850757

Product name

Anti-HJURP

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human HJURP, Gene description: Holliday junction recognition protein, Alternative Gene Names: DKFZp762E1312, FAKTS, hFLEG1, URLC9, Validated applications: IHC, ICC, Uniprot ID: Q8NCD3, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.2 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

The histone H3/H4 chaperone CHAF1B prevents the mislocalization of CENP-A for chromosomal stability

Shrestha R, Balachandra V, Kim J, Rossi A, Vadlamani P, Sethi S, Ozbun L, Lin S, Cheng K, Chari R, Karpova T, Pegoraro G, Foltz D, Caplen N, Basrai M
Journal of Cell Science 2023;136(10)

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DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network

Hammond C, Bao H, Hendriks I, Carraro M, García-Nieto A, Liu Y, Reverón-Gómez N, Spanos C, Chen L, Rappsilber J, Nielsen M, Patel D, Huang H, Groth A
Molecular Cell 2021;81(12):2533-2548.e9

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CENP-A overexpression promotes distinct fates in human cells, depending on p53 status

Jeffery D, Gatto A, Podsypanina K, Renaud-Pageot C, Ponce Landete R, Bonneville L, Dumont M, Fachinetti D, Almouzni G
Communications Biology 2021;4(1)

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HJURP antagonizes CENP-A mislocalization driven by the H3.3 chaperones HIRA and DAXX

Bosco G, Nye J, Sturgill D, Athwal R, Dalal Y
PLOS ONE 2018;13(10):e0205948

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Essential role for centromeric factors following p53 loss and oncogenic transformation

Filipescu D, Naughtin M, Podsypanina K, Lejour V, Wilson L, Gurard-Levin Z, Orsi G, Simeonova I, Toufektchan E, Attardi L, Toledo F, Almouzni G
Genes & Development 2017;31(5):463-480

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A Non-Synonymous Single Nucleotide Polymorphism in the HJURP Gene Associated with Susceptibility to Hepatocellular Carcinoma among Chinese

Zhang Z, Huang W, Zhang H, Hao Y, Xu X, Zhai Y, Wang S, Li Y, Ma F, Li Y, Wang Z, Zhang Y, Zhang X, Liang R, Wei Z, Cui Y, Li Y, Yu X, Ji H, He F, Xie W, Zhou G
PLOS ONE 2016;11(2):e0148618

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Prognostic Significance of EDN/RB, HJURP, p60/CAF-1 and PDLI4, Four New Markers in High-Grade Gliomas

Jiang T, de Tayrac M, Saikali S, Aubry M, Bellaud P, Boniface R, Quillien V, Mosser J
PLoS ONE 2013;8(9):e73332

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The expression level of HJURP has an independent prognostic impact and predicts the sensitivity to radiotherapy in breast cancer

Hu Z, Huang G, Sadanandam A, Gu S, Lenburg M, Pai M, Bayani N, Blakely E, Gray J, Mao J
Breast Cancer Research 2010;12(2)

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HJURP binds CENP-A via a highly conserved N-terminal domain and mediates its deposition at centromeres

Shuaib M, Ouararhni K, Dimitrov S, Hamiche A
Proceedings of the National Academy of Sciences 2010;107(4):1349-1354