CABT-46493MH

CD58 antibody from Creative Diagnostics
LFA3
Immunoprecipitation
Recommended by provider
Immunohistochemistry
Recommended by provider
Flow cytometry
Recommended by provider

Antibody data

Product number
CABT-46493MH
Provider
Creative Diagnostics
Proper citation
Creative Diagnostics Cat#CABT-46493MH, RRID:AB_2529030
Product name
Anti-CD58 monoclonal antibody, clone MEM-63
Provider product page
Creative Diagnostics - CABT-46493MH
Antibody type
Monoclonal
Description
CD58, or LFA-3, is a membrane glycoprotein of 55-70kD. It occurs in two forms, one transmembrane with a cytoplasmic domain, the other form anchored in the membrane via a glycosylphosphatidylinositol tail. The complete amino acid sequence of both forms has been deduced from cDNA. It is heavily N-glycosylated. CD58 is a cell adhesion molecule which plays a critical role in facilitation of antigen specific recognition through interaction with CD2 on T lymphocytes. It is a member of the immunoglobulin superfamily of molecules.CD58 has a wide tissue distribution, being present on erythrocytes, platelets, monocytes, a subset of lymphocytes, bone marrow cells, epithelium and endothelial cells. There are approximately 5,000 CD58 molecules on each erythrocyte. There is reduced expression of CD58 on haemopoietic cells in individuals with paroxysmal nocturnal haemoglobinuria. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Antibody clone number
MEM-63
Vial size
100  mg
Storage
in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Handling
The antibody solution should be gently mixed before use.
Provider Type Product Number
- No reagents -