322502

antibody from BioLegend
Targeting: CD58 LFA3
Provider product page for 322502

Antibody data

Product number
322502 - Provider product page
Provider
BioLegend
Product name
Purified anti-human CD58
Antibody type
Monoclonal
Antigen
CD58
Description
CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms on cell surface. CD58 is xpressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of its cognate ligand, CD2, on the T cell surface. The HCD58 antibody recognizes human CD58 and has been shown to be useful for flow cytometry.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4°C.
CD58 protein structure - 322502 shown in red.