BS7412

antibody from Bioworld Technology, Inc
Targeting: POSTN OSF-2, periostin, PN
Provider product page for BS7412
Western blot
Immunohistochemistry

Antibody data

Product number
BS7412 - Provider product page
Provider
Bioworld Technology, Inc
Product name
POSTN polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human POSTN.
Description
Periostin (PN), also designated osteoblast-specific factor 2 (OSF-2), is a disulfide linked protein originally isolated as a osteoblast-specific factor. Periostin is a secreted protein that binds heparin and functions as a ligand for alpha(V)beta(3) and alpha(V)beta(5) integrins. In preosteoblasts, Periostin acts as a cell adhesion molecule and plays a role in osteoblast recruitment, spreading and attachment. Periostin is mainly detected in lower gastrointestinal tract, aorta, stomach, placenta, uterus and breast tissues but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression of Periostin is increased by bone morphogenetic protein (BMP2) and transforming growth factor ÉÇ 1(TGF ÉÇ 1). Periostin contains a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain, which shows homology with the insect protein fasciclin, and a C-terminal domain.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
POSTN protein structure - BS7412 shown in red.