MAB3548

antibody from R&D Systems

Targeting: POSTN OSF-2, periostin, PN

Western blot (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

MAB3548

Provider

R&D Systems

Product name

Human/Mouse Periostin/OSF-2 Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects mouse Periostin/OSF-2 in direct ELISAs and Western blots.

Reactivity

Human, Mouse

Host

Rat

Conjugate

Unconjugated

Antigen sequence

NP_056599


Isotype

IgG

Antibody clone number

345613

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Therapeutic Effect of Novel Single-Stranded RNAi Agent Targeting Periostin in Eyes with Retinal Neovascularization.

Nakama T, Yoshida S, Ishikawa K, Kubo Y, Kobayashi Y, Zhou Y, Nakao S, Hisatomi T, Ikeda Y, Takao K, Yoshikawa K, Matsuda A, Ono J, Ohta S, Izuhara K, Kudo A, Sonoda KH, Ishibashi T
Molecular therapy. Nucleic acids 2017 Mar 17;6:279-289

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Histamine contributes to tissue remodeling via periostin expression.

Yang L, Murota H, Serada S, Fujimoto M, Kudo A, Naka T, Katayama I
The Journal of investigative dermatology 2014 Aug;134(8):2105-2113

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ß3 integrin modulates transforming growth factor beta induced (TGFBI) function and paclitaxel response in ovarian cancer cells.

Tumbarello DA, Temple J, Brenton JD
Molecular cancer 2012 May 28;11:36

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TRPC3-mediated Ca2+ influx contributes to Rac1-mediated production of reactive oxygen species in MLP-deficient mouse hearts.

Kitajima N, Watanabe K, Morimoto S, Sato Y, Kiyonaka S, Hoshijima M, Ikeda Y, Nakaya M, Ide T, Mori Y, Kurose H, Nishida M
Biochemical and biophysical research communications 2011 May 27;409(1):108-13

Immunocytochemistry

Supportive validation

Submitted by

R&D Systems (provider)

Main image

Experimental details

Periostin/OSF-2 in Human Osteocytes. Periostin/OSF-2 was detected in immersion fixed human osteocytes using Rat Anti-Human/Mouse Periostin/OSF-2 Monoclonal Antibody (Catalog # MAB3548) at 10 µg/mL for 3 hours at room temperature. Cells were stained red and counterstained with DAPI (blue).