28580-1-AP

antibody from Proteintech Group

Targeting: NOTCH2

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

28580-1-AP

Provider

Proteintech Group

Product name

NOTCH2 antibody

Antibody type

Polyclonal

Description

NOTCH2 antibody (Cat. #28580-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human and has been validated for the following applications: WB,ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Identification of SCAMP2 as a regulator of NOTCH signaling in cisplatin resistance through a novel prognostic model for bladder cancer.

Cai L, Zhang S, Zheng F, Ji F, Wang J, Shi L, Chao L, Wang X, Zhang J, Chen Z
Frontiers in immunology 2025;16:1573412

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miR-34c-5p targets Notch2 to promote fracture healing.

Li K, Liu G, Chen F, Sun X, Liu B
Journal of orthopaedic surgery and research 2025 Oct 24;20(1):924

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Combined therapy with DR5-targeting antibody-drug conjugate and CDK inhibitors as a strategy for advanced colorectal cancer.

Zhou D, Tang E, Wang W, Xiao Y, Huang J, Liu J, Zheng C, Zhang K, Hu R, Wang F, Xiong P, Chu X, Li W, Liu D, Zeng X, Zheng D, Wang L, Zheng Y, Zhang S
Cell reports. Medicine 2025 Jun 17;6(6):102158

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YTHDF3 drives tumor growth and metastasis by recruiting eIF4B to promote Notch2 translation in breast cancer.

Chen H, Lin L, Qiao Z, Pei Y, Gao Y, Lou K, Yang L, Li C, He Y, Bai J, Zhang G
Cancer letters 2025 Apr 1;614:217534

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The MEF2A/SNHG16/miR-425-5p/NOTCH2 axis induces gemcitabine resistance by inhibiting ferroptosis in the starving bladder tumor microenvironment.

Zhou X, Zhang C, Yu H, Feng Z, Bai X, Mei Y, Li L, Li X, Gou X, Deng Y
Cellular signalling 2024 Oct;122:111337

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ASH2L Mediates Epidermal Differentiation and Hair Follicle Morphogenesis through H3K4me3 Modification.

Wang Q, Zeng S, Liang Y, Zhou R, Wang D
The Journal of investigative dermatology 2024 Nov;144(11):2406-2416.e10

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LINC00460 promotes neuroblastoma tumorigenesis and cisplatin resistance by targeting miR-149-5p/DLL1 axis and activating Notch pathway in vitro and in vivo.

Xu Y, Qiu Z, Chen J, Huang L, Zhang J, Lin J
Drug delivery and translational research 2024 Jul;14(7):2003-2018

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microRNA-18a-5p promotes vascular smooth muscle cell phenotypic switch by targeting Notch2 as therapeutic targets in vein grafts restenosis.

Zhan X, Zhong CM, Tang H, Xiao H, Guo Y, Zhang C, Qu C, Wang X, Huang C
European journal of pharmacology 2024 Dec 15;985:177097

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GHITM regulates malignant phenotype and sensitivity to PD-1 blockade of renal cancer cells via Notch signalling.

Huang S, Liu J, Hu J, Hou Y, Hu M, Zhang B, Luo H, Fu S, Chen Y, Liu X, Chen Z, Wang L
Journal of cellular and molecular medicine 2024 Apr;28(8):e18290

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[DTX2 overexpression promotes migration and invasion of colorectal cancer cells through the Notch2/Akt axis].

Ma Z, Zhao X, Zhang X, Xu G, Liu F
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Mar 20;43(3):340-348

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A comprehensive role evaluation and mechanism exploration of POGLUT2 in pan-cancer.

Xu X, Xie G, Xie M, Liu Q
Frontiers in oncology 2022;12:962540

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Evaluation of NOTCH family genes' expression and prognostic value in prostate cancer.

Qing Y, Wang Y, Hu C, Zhang H, Huang Y, Zhang Z, Ma T, Zhang S, Li K
Translational andrology and urology 2022 May;11(5):627-642

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APEX2-Mediated Proximity Labeling Resolves the DDIT4-Interacting Proteome.

Naki M, Gourdomichali O, Zonke K, Kattan FG, Makridakis M, Kontostathi G, Vlahou A, Doxakis E
International journal of molecular sciences 2022 May 6;23(9)

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Therapeutic targeting m6A-guided miR-146a-5p signaling contributes to the melittin-induced selective suppression of bladder cancer.

Yan R, Dai W, Wu R, Huang H, Shu M
Cancer letters 2022 May 28;534:215615

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GALNT2 promotes cell proliferation, migration, and invasion by activating the Notch/Hes1-PTEN-PI3K/Akt signaling pathway in lung adenocarcinoma.

Wang W, Sun R, Zeng L, Chen Y, Zhang N, Cao S, Deng S, Meng X, Yang S
Life sciences 2021 Jul 1;276:119439

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SLC6A8 is involved in the progression of non-small cell lung cancer through the Notch signaling pathway.

Feng Y, Guo X, Tang H
Annals of translational medicine 2021 Feb;9(3):264