Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS60452 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- TRPM8 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human TRPM8.
- Description
- TRPM8 (transient receptor potential cation channel, subfamily M, member 8), also known as TRPP8 or LTRPC6, is a 1,104 amino acid multi-pass membrane protein that belongs to the TRP family of regulatory channel proteins. Expressed at high levels in prostate, TRPM8 functions as a receptor-activated cation channel that is permeable to monovalent cations (such as sodium and potassium) and divalent Ca2+ and is involved in the detection of temperature sensations (such as the feeling of coolness) throughout the body. TRPM8 is overexpressed in prostate tumors, as well as in colon, breast and lung cancers, suggesting an important role for TRPM8 in tumorigenesis.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of TRPM8 pAb at 1:500 dilutionLane1:MCF-7 cell lysateLane2:NIH-3T3 cell lysateLane3:H9C2 cell lysate