Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Flow cytometry [2]
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- Product number
- MA1-10270 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CD64 Monoclonal Antibody (10.1)
- Antibody type
- Monoclonal
- Antigen
- Purifed from natural sources
- Description
- This antibody recognizes an extracellular epitope on CD64/FcgammaRI, a 72 kDa single chain type I glycoprotein, that is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The epitope is sensitive to formalin fixation.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 10.1
- Vial size
- 100 µg
- Concentration
- 1 mg/mL
- Storage
- 4° C, do not freeze
Submitted references Pivotal Role for CD16+ Monocytes in Immune Surveillance of the Central Nervous System.
Plasmacytoid dendritic cells and their Toll-like receptor 9 expression selectively decrease with age.
Copy number of FCGR3B, which is associated with systemic lupus erythematosus, correlates with protein expression and immune complex uptake.
Engagement of CD83 ligand induces prolonged expansion of CD8+ T cells and preferential enrichment for antigen specificity.
Flow cytometry identification and characterization of mononuclear cell subsets in the neotropical primate Saimiri sciureus (squirrel monkey).
Prognostic significance of CD56 antigen expression in acute myeloid leukemia.
Waschbisch A, Schröder S, Schraudner D, Sammet L, Weksler B, Melms A, Pfeifenbring S, Stadelmann C, Schwab S, Linker RA
Journal of immunology (Baltimore, Md. : 1950) 2016 Feb 15;196(4):1558-67
Journal of immunology (Baltimore, Md. : 1950) 2016 Feb 15;196(4):1558-67
Plasmacytoid dendritic cells and their Toll-like receptor 9 expression selectively decrease with age.
Garbe K, Bratke K, Wagner S, Virchow JC, Lommatzsch M
Human immunology 2012 May;73(5):493-7
Human immunology 2012 May;73(5):493-7
Copy number of FCGR3B, which is associated with systemic lupus erythematosus, correlates with protein expression and immune complex uptake.
Willcocks LC, Lyons PA, Clatworthy MR, Robinson JI, Yang W, Newland SA, Plagnol V, McGovern NN, Condliffe AM, Chilvers ER, Adu D, Jolly EC, Watts R, Lau YL, Morgan AW, Nash G, Smith KG
The Journal of experimental medicine 2008 Jul 7;205(7):1573-82
The Journal of experimental medicine 2008 Jul 7;205(7):1573-82
Engagement of CD83 ligand induces prolonged expansion of CD8+ T cells and preferential enrichment for antigen specificity.
Hirano N, Butler MO, Xia Z, Ansén S, von Bergwelt-Baildon MS, Neuberg D, Freeman GJ, Nadler LM
Blood 2006 Feb 15;107(4):1528-36
Blood 2006 Feb 15;107(4):1528-36
Flow cytometry identification and characterization of mononuclear cell subsets in the neotropical primate Saimiri sciureus (squirrel monkey).
Contamin H, Loizon S, Bourreau E, Michel JC, Garraud O, Mercereau-Puijalon O, Behr C
Journal of immunological methods 2005 Feb;297(1-2):61-71
Journal of immunological methods 2005 Feb;297(1-2):61-71
Prognostic significance of CD56 antigen expression in acute myeloid leukemia.
Di Bona E, Sartori R, Zambello R, Guercini N, Madeo D, Rodeghiero F
Haematologica 2002 Mar;87(3):250-6
Haematologica 2002 Mar;87(3):250-6
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Flow cytometry surface staining pattern of human peripheral blood stained using anti-human CD64 (10.1) purified Monoclonal antibody (Product # MA1-10270) (concentration in sample 4 µg/mL) GAM APC.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Separation of human monocytes (red-filled) from CD64 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD64 (10.1) purified Monoclonal antibody (Product # MA1-10270) (concentration in sample 4 µg/mL) GAM APC.