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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- 305004 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#305004, RRID:AB_314488
- Product name
- Biotin anti-human CD64
- Antibody type
- Monoclonal
- Antigen
- CD64
- Description
- CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Biotin
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C. Do not freeze.
Submitted references Specificity and affinity of human Fcgamma receptors and their polymorphic variants for human IgG subclasses.
C-reactive protein and annexin A5 bind to distinct sites of negatively charged phospholipids present in oxidized low-density lipoprotein.
Bruhns P, Iannascoli B, England P, Mancardi DA, Fernandez N, Jorieux S, Daëron M
Blood 2009 Apr 16;113(16):3716-25
Blood 2009 Apr 16;113(16):3716-25
C-reactive protein and annexin A5 bind to distinct sites of negatively charged phospholipids present in oxidized low-density lipoprotein.
van Tits L, de Graaf J, Toenhake H, van Heerde W, Stalenhoef A
Arteriosclerosis, thrombosis, and vascular biology 2005 Apr;25(4):717-22
Arteriosclerosis, thrombosis, and vascular biology 2005 Apr;25(4):717-22
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Whole blood monocytes stained with 10.1 FITC
- Conjugate
- Biotin
