305014

antibody from BioLegend

Targeting: FCGR1A CD64, CD64A

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

305014

Provider

BioLegend

Proper citation

BioLegend Cat#305014, RRID:AB_1595428

Product name

APC anti-human CD64

Antibody type

Monoclonal

Antigen

CD64

Description

CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).

Reactivity

Human, Simian

Host

Mouse

Conjugate

Red dye

Isotype

IgG

Vial size

100 tests

Storage

The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

References

Submitted references

Specificity and affinity of human Fcgamma receptors and their polymorphic variants for human IgG subclasses.

Bruhns P, Iannascoli B, England P, Mancardi DA, Fernandez N, Jorieux S, Daëron M
Blood 2009 Apr 16;113(16):3716-25

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C-reactive protein and annexin A5 bind to distinct sites of negatively charged phospholipids present in oxidized low-density lipoprotein.

van Tits L, de Graaf J, Toenhake H, van Heerde W, Stalenhoef A
Arteriosclerosis, thrombosis, and vascular biology 2005 Apr;25(4):717-22

Flow cytometry

Supportive validation

Submitted by

BioLegend (provider)

Main image

Experimental details

Human peripheral blood monocytes stained with 10.1 APC

Conjugate

Red dye