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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Product number
- 305015 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#305015, RRID:AB_1595640
- Product name
- LEAF™ anti-human CD64 [10.1]
- Antibody type
- Monoclonal
- Antigen
- CD64
- Description
- CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 50 µg
- Concentration
- 1 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C. This LEAF™ solution contains no preservative; handle under aseptic conditions.
Submitted references Specificity and affinity of human Fcgamma receptors and their polymorphic variants for human IgG subclasses.
C-reactive protein and annexin A5 bind to distinct sites of negatively charged phospholipids present in oxidized low-density lipoprotein.
Bruhns P, Iannascoli B, England P, Mancardi DA, Fernandez N, Jorieux S, Daëron M
Blood 2009 Apr 16;113(16):3716-25
Blood 2009 Apr 16;113(16):3716-25
C-reactive protein and annexin A5 bind to distinct sites of negatively charged phospholipids present in oxidized low-density lipoprotein.
van Tits L, de Graaf J, Toenhake H, van Heerde W, Stalenhoef A
Arteriosclerosis, thrombosis, and vascular biology 2005 Apr;25(4):717-22
Arteriosclerosis, thrombosis, and vascular biology 2005 Apr;25(4):717-22
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