10338-1-AP
antibody from Proteintech Group
Targeting: MLPH
exophilin-3, l(1)-3Rk, l1Rk3, ln, Slac-2a
Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 10338-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10338-1-AP, RRID:AB_2146104
- Product name
- Melanophilin antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Melanophilin antibody (Cat. #10338-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Regulation of Melanophilin (Mlph) gene expression by the glucocorticoid receptor (GR).
MLPH Accelerates the Epithelial-Mesenchymal Transition in Prostate Cancer.
A novel function of Prohibitin on melanosome transport in melanocytes.
16-Kauren-2-beta-18,19-triol inhibits melanosome transport in melanocytes by down-regulation of melanophilin expression.
Identification of MicroRNA Targeting Mlph and Affecting Melanosome Transport.
Inhibitory effect of 2-methyl-naphtho[1,2,3-de]quinolin-8-one on melanosome transport and skin pigmentation.
Patients with Griscelli syndrome and normal pigmentation identify RAB27A mutations that selectively disrupt MUNC13-4 binding.
Cellular and clinical report of new Griscelli syndrome type III cases.
Differential gene expression in normal esophagus and Barrett's esophagus.
Knockdown of myosin Va isoforms by RNAi as a tool to block melanosome transport in primary human melanocytes.
A novel missense mutation (G43S) in the switch I region of Rab27A causing Griscelli syndrome.
Myung CH, Lee JE, Jo CS, Park JI, Hwang JS
Scientific reports 2021 Aug 19;11(1):16813
Scientific reports 2021 Aug 19;11(1):16813
MLPH Accelerates the Epithelial-Mesenchymal Transition in Prostate Cancer.
Zhang T, Sun Y, Zheng T, Wang R, Jia D, Zhang W
OncoTargets and therapy 2020;13:701-708
OncoTargets and therapy 2020;13:701-708
A novel function of Prohibitin on melanosome transport in melanocytes.
Jo CS, Park HI, Jung HJ, Park JI, Lee JE, Myung CH, Hwang JS
Theranostics 2020;10(9):3880-3891
Theranostics 2020;10(9):3880-3891
16-Kauren-2-beta-18,19-triol inhibits melanosome transport in melanocytes by down-regulation of melanophilin expression.
Myung CH, Kim K, Park JI, Lee JE, Lee JA, Hong SC, Lim KM, Hwang JS
Journal of dermatological science 2020 Feb;97(2):101-108
Journal of dermatological science 2020 Feb;97(2):101-108
Identification of MicroRNA Targeting Mlph and Affecting Melanosome Transport.
Lee JA, Hwang SJ, Hong SC, Myung CH, Lee JE, Park JI, Hwang JS
Biomolecules 2019 Jul 8;9(7)
Biomolecules 2019 Jul 8;9(7)
Inhibitory effect of 2-methyl-naphtho[1,2,3-de]quinolin-8-one on melanosome transport and skin pigmentation.
Park JI, Lee HY, Lee JE, Myung CH, Hwang JS
Scientific reports 2016 Jul 6;6:29189
Scientific reports 2016 Jul 6;6:29189
Patients with Griscelli syndrome and normal pigmentation identify RAB27A mutations that selectively disrupt MUNC13-4 binding.
Cetica V, Hackmann Y, Grieve S, Sieni E, Ciambotti B, Coniglio ML, Pende D, Gilmour K, Romagnoli P, Griffiths GM, Aricò M
The Journal of allergy and clinical immunology 2015 May;135(5):1310-8.e1
The Journal of allergy and clinical immunology 2015 May;135(5):1310-8.e1
Cellular and clinical report of new Griscelli syndrome type III cases.
Westbroek W, Klar A, Cullinane AR, Ziegler SG, Hurvitz H, Ganem A, Wilson K, Dorward H, Huizing M, Tamimi H, Vainshtein I, Berkun Y, Lavie M, Gahl WA, Anikster Y
Pigment cell & melanoma research 2012 Jan;25(1):47-56
Pigment cell & melanoma research 2012 Jan;25(1):47-56
Differential gene expression in normal esophagus and Barrett's esophagus.
Wang J, Qin R, Ma Y, Wu H, Peters H, Tyska M, Shaheen NJ, Chen X
Journal of gastroenterology 2009;44(9):897-911
Journal of gastroenterology 2009;44(9):897-911
Knockdown of myosin Va isoforms by RNAi as a tool to block melanosome transport in primary human melanocytes.
Van Gele M, Geusens B, Schmitt AM, Aguilar L, Lambert J
The Journal of investigative dermatology 2008 Oct;128(10):2474-84
The Journal of investigative dermatology 2008 Oct;128(10):2474-84
A novel missense mutation (G43S) in the switch I region of Rab27A causing Griscelli syndrome.
Westbroek W, Tuchman M, Tinloy B, De Wever O, Vilboux T, Hertz JM, Hasle H, Heilmann C, Helip-Wooley A, Kleta R, Gahl WA
Molecular genetics and metabolism 2008 Jun;94(2):248-54
Molecular genetics and metabolism 2008 Jun;94(2):248-54
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A375 cells were subjected to SDS PAGE followed by western blot with 10338-1-AP(MLPH antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using MLPH antibody 10338-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line