BS8330

antibody from Bioworld Technology, Inc

Targeting: MLPH exophilin-3, l(1)-3Rk, l1Rk3, ln, Slac-2a

Immunohistochemistry

Antibody data

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Validation data

Product number: BS8330 - Provider product page
Provider: Bioworld Technology, Inc
Product name: MLPH polyclonal antibody
Antibody type: Polyclonal
Antigen: Recombinant full length Human MLPH.
Description: Slac2-a (for synaptotagmin-like protein (Slp) homolog lacking C2 domains-a) links Rab27A on melanosomes with Myosin VA in melanocytes. Slac2-a binds Myosin VA through a C-terminal region and GTP-bound Rab27A through its synaptotagmin-like protein homology domain (SHD), which is located near the N-terminus. The transport of pigment and cytotoxic granules in melanocytes requires the stable formation of this complex, and thus mutations in the binding domains of the three protein components may cause albinism and/or severe immune disorders.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

MLPH protein structure - BS8330 shown in red.