Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10482-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10482-1-AP, RRID:AB_2301639
- Product name
- SF3B4 antibody
- Antibody type
- Polyclonal
- Description
- SF3B4 antibody (Cat. #10482-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Human stem cell model of neural crest cell differentiation reveals a requirement of SF3B4 in survival, maintenance, and differentiation.
SF3B4 downregulation restrains lung adenocarcinoma tumorigenesis via 5' alternative splicing of KAT2A.
SETDB1 promotes progression through upregulation of SF3B4 expression and regulates the immunity in ovarian cancer.
Sf3b4 mutation in Xenopus tropicalis causes RNA splicing defects followed by massive gene dysregulation that disrupt cranial neural crest development.
LncRNA BC promotes lung adenocarcinoma progression by modulating IMPAD1 alternative splicing.
SF3B4 promotes Twist1 expression and clear cell renal cell carcinoma progression by facilitating the export of KLF 16 mRNA from the nucleus to the cytoplasm.
Multi-omics approach reveals posttranscriptionally regulated genes are essential for human pluripotent stem cells.
The splicing factor SF3B4 drives proliferation and invasion in cervical cancer by regulating SPAG5.
SF3B4 promotes ovarian cancer progression by regulating alternative splicing of RAD52.
Remodeling of the m(6)A landscape in the heart reveals few conserved post-transcriptional events underlying cardiomyocyte hypertrophy.
Novel RNA-Affinity Proteogenomics Dissects Tumor Heterogeneity for Revealing Personalized Markers in Precision Prognosis of Cancer.
Griffin C, Saint-Jeannet JP
bioRxiv : the preprint server for biology 2024 May 2;
bioRxiv : the preprint server for biology 2024 May 2;
SF3B4 downregulation restrains lung adenocarcinoma tumorigenesis via 5' alternative splicing of KAT2A.
Qu A, Han B, Hua M, Wang C, Li T
Scientific reports 2024 Jan 2;14(1):30
Scientific reports 2024 Jan 2;14(1):30
SETDB1 promotes progression through upregulation of SF3B4 expression and regulates the immunity in ovarian cancer.
Yang H, Sui L, Cai C, Chu H, Diao Y
Journal of ovarian research 2024 Feb 5;17(1):34
Journal of ovarian research 2024 Feb 5;17(1):34
Sf3b4 mutation in Xenopus tropicalis causes RNA splicing defects followed by massive gene dysregulation that disrupt cranial neural crest development.
Griffin C, Coppenrath K, Khan D, Lin Z, Horb M, Saint-Jeannet JP
bioRxiv : the preprint server for biology 2024 Feb 2;
bioRxiv : the preprint server for biology 2024 Feb 2;
LncRNA BC promotes lung adenocarcinoma progression by modulating IMPAD1 alternative splicing.
Chen QW, Cai QQ, Yang Y, Dong S, Liu YY, Chen ZY, Kang CL, Qi B, Dong YW, Wu W, Zhuang LP, Shen YH, Meng ZQ, Wu XZ
Clinical and translational medicine 2023 Jan;13(1):e1129
Clinical and translational medicine 2023 Jan;13(1):e1129
SF3B4 promotes Twist1 expression and clear cell renal cell carcinoma progression by facilitating the export of KLF 16 mRNA from the nucleus to the cytoplasm.
Yang Z, Wang YX, Wen JK, Gao HT, Han ZW, Qi JC, Gu JF, Zhao CM, Zhang H, Shi B, Wang DD, Wang XL, Qu CB
Cell death & disease 2023 Jan 13;14(1):26
Cell death & disease 2023 Jan 13;14(1):26
Multi-omics approach reveals posttranscriptionally regulated genes are essential for human pluripotent stem cells.
Iwasaki M, Kawahara Y, Okubo C, Yamakawa T, Nakamura M, Tabata T, Nishi Y, Narita M, Ohta A, Saito H, Yamamoto T, Nakagawa M, Yamanaka S, Takahashi K
iScience 2022 May 20;25(5):104289
iScience 2022 May 20;25(5):104289
The splicing factor SF3B4 drives proliferation and invasion in cervical cancer by regulating SPAG5.
Li Y, Diao Y, Wang Z, Wang S, Peng J, Kong B
Cell death discovery 2022 Jul 19;8(1):326
Cell death discovery 2022 Jul 19;8(1):326
SF3B4 promotes ovarian cancer progression by regulating alternative splicing of RAD52.
Diao Y, Li Y, Wang Z, Wang S, Li P, Kong B
Cell death & disease 2022 Feb 24;13(2):179
Cell death & disease 2022 Feb 24;13(2):179
Remodeling of the m(6)A landscape in the heart reveals few conserved post-transcriptional events underlying cardiomyocyte hypertrophy.
Hinger SA, Wei J, Dorn LE, Whitson BA, Janssen PML, He C, Accornero F
Journal of molecular and cellular cardiology 2021 Feb;151:46-55
Journal of molecular and cellular cardiology 2021 Feb;151:46-55
Novel RNA-Affinity Proteogenomics Dissects Tumor Heterogeneity for Revealing Personalized Markers in Precision Prognosis of Cancer.
Wang L, Wrobel JA, Xie L, Li D, Zurlo G, Shen H, Yang P, Wang Z, Peng Y, Gunawardena HP, Zhang Q, Chen X
Cell chemical biology 2018 May 17;25(5):619-633.e5
Cell chemical biology 2018 May 17;25(5):619-633.e5
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10482-1-AP(SF3B4 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SF3B4 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SF3B4. This antibody recognizes human, mouse, rat antigen. The SF3B4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.