Tissue expression
Cell line expression
Protein structure
VPS72
Vacuolar protein sorting 72 homologSwc2, TCFL1, YL-1, YL1
The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
Top validated antibodies |
|||||
Proteintech Group | 15143-1-AP | 2 references | Polyclonal |
WB
EL
IP
|
|
Boster Biological Technology | A11502-1 | Polyclonal |
WB
EL
ICC
IHC |
||
Affinity Biosciences | AF0508 | Polyclonal |
WB
EL
ICC
IHC |
||
Cusabio Biotech Co., Ltd | CSB-PA050222 | Polyclonal |
WB
EL
ICC
IHC |
||
LSBio | LS-C800552 | Polyclonal |
WB
EL
ICC
IHC |
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider