Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [6]
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- Product number
- NBP1-83475 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-83475, RRID:AB_11036653
- Product name
- Rabbit Polyclonal FAM98B Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human FAM98B antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references hCLE/C14orf166 associates with DDX1-HSPC117-FAM98B in a novel transcription-dependent shuttling RNA-transporting complex.
Analysis of orthologous groups reveals archease and DDX1 as tRNA splicing factors.
The mammalian tRNA ligase complex mediates splicing of XBP1 mRNA and controls antibody secretion in plasma cells.
Pérez-González A, Pazo A, Navajas R, Ciordia S, Rodriguez-Frandsen A, Nieto A
PloS one 2014;9(3):e90957
PloS one 2014;9(3):e90957
Analysis of orthologous groups reveals archease and DDX1 as tRNA splicing factors.
Popow J, Jurkin J, Schleiffer A, Martinez J
Nature 2014 Jul 3;511(7507):104-7
Nature 2014 Jul 3;511(7507):104-7
The mammalian tRNA ligase complex mediates splicing of XBP1 mRNA and controls antibody secretion in plasma cells.
Jurkin J, Henkel T, Nielsen AF, Minnich M, Popow J, Kaufmann T, Heindl K, Hoffmann T, Busslinger M, Martinez J
The EMBO journal 2014 Dec 17;33(24):2922-36
The EMBO journal 2014 Dec 17;33(24):2922-36
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: FAM98B Antibody [NBP1-83475] - Analysis in control (vector only transfected HEK293T lysate) and FAM98B over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: FAM98B Antibody [NBP1-83475] - Analysis using Anti-FAM98B antibody NBP1-83475 (A) shows similar pattern to independent antibody NBP1-83474 (B).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475] - Staining of human rectum shows strong membranous and nuclear positivity in glandular cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475] - Staining of human cerebral cortex, colon, lymph node and testis using Anti-FAM98B antibody NBP1-83475 (A) shows similar protein distribution across tissues to independent antibody NBP1-83474 (B).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475] - Staining of human colon.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475] - Staining of human lymph node.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475] - Staining of human testis.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: FAM98B Antibody [NBP1-83475] - Staining of human cerebral cortex.