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- References [4]
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- Product number
- ABIN2846206 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-BCL2-Related Ovarian Killer (BOK) (BH3 Domain) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- BH3 Domain
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Stress via p53 pathway causes apoptosis by mitochondrial Noxa upregulation in doxorubicin-treated neuroblastoma cells.
Membrane translocation and oligomerization of hBok are triggered in response to apoptotic stimuli and Bnip3.
BOK and NOXA are essential mediators of p53-dependent apoptosis.
Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members.
Kurata K, Yanagisawa R, Ohira M, Kitagawa M, Nakagawara A, Kamijo T
Oncogene 2008 Jan 31;27(6):741-54
Oncogene 2008 Jan 31;27(6):741-54
Membrane translocation and oligomerization of hBok are triggered in response to apoptotic stimuli and Bnip3.
Gao S, Fu W, Dürrenberger M, De Geyter C, Zhang H
Cellular and molecular life sciences : CMLS 2005 May;62(9):1015-24
Cellular and molecular life sciences : CMLS 2005 May;62(9):1015-24
BOK and NOXA are essential mediators of p53-dependent apoptosis.
Yakovlev AG, Di Giovanni S, Wang G, Liu W, Stoica B, Faden AI
The Journal of biological chemistry 2004 Jul 2;279(27):28367-74
The Journal of biological chemistry 2004 Jul 2;279(27):28367-74
Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members.
Hsu SY, Kaipia A, McGee E, Lomeli M, Hsueh AJ
Proceedings of the National Academy of Sciences of the United States of America 1997 Nov 11;94(23):12401-6
Proceedings of the National Academy of Sciences of the United States of America 1997 Nov 11;94(23):12401-6
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Supportive validation
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- antibodies-online (provider)
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- Experimental details
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
