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- Antibody Data
- Antigen structure
- References [9]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- HPA035981 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA035981, RRID:AB_10669664
- Product name
- Anti-PDCD1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human PDCD1, Gene description: programmed cell death 1, Alternative Gene Names: CD279, hSLE1, PD1, SLEB2, Validated applications: IHC, WB, Uniprot ID: Q15116, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references TAK1 expression is associated with increased PD-L1 and decreased cancer-specific survival in microsatellite-stable colorectal cancer.
Tumor-associated macrophages and Tregs influence and represent immune cell infiltration of muscle-invasive bladder cancer and predict prognosis
Neoadjuvant Chemoradiotherapy for Oral Cavity Cancer: Predictive Factors for Response and Interim Analysis of the Prospective INVERT-Trial
The prognostic significance of tumor-infiltrating lymphocytes in cervical cancer
Relationship between immune checkpoint proteins, tumour microenvironment characteristics, and prognosis in primary operable colorectal cancer.
Clinicopathologic correlates of MYD88 L265P mutation and programmed cell death (PD-1) pathway in primary central nervous system lymphoma
A case report of clonal EBV-like memory CD4+ T cell activation in fatal checkpoint inhibitor-induced encephalitis
CTLA-4+PD-1− Memory CD4+ T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques
PD-L1 expression and its relationship with oncogenic drivers in non-small cell lung cancer (NSCLC).
Galbraith NJ, Quinn JA, Al-Badran SS, Pennel KAF, Hillson LVS, Hatthakarnkul P, McKenzie M, Maka N, Loi L, Frixou M, Steele CW, Roxburgh CS, Horgan PG, McMillan DC, Edwards J
Translational oncology 2024 Oct;48:102064
Translational oncology 2024 Oct;48:102064
Tumor-associated macrophages and Tregs influence and represent immune cell infiltration of muscle-invasive bladder cancer and predict prognosis
Koll F, Banek S, Kluth L, Köllermann J, Bankov K, Chun F, Wild P, Weigert A, Reis H
Journal of Translational Medicine 2023;21(1)
Journal of Translational Medicine 2023;21(1)
Neoadjuvant Chemoradiotherapy for Oral Cavity Cancer: Predictive Factors for Response and Interim Analysis of the Prospective INVERT-Trial
von der Grün J, Winkelmann R, Burck I, Martin D, Rödel F, Wild P, Bankov K, Weigert A, Kur I, Brandts C, Filmann N, Issing C, Thönissen P, Tanneberger A, Rödel C, Ghanaati S, Balermpas P
Frontiers in Oncology 2022;12
Frontiers in Oncology 2022;12
The prognostic significance of tumor-infiltrating lymphocytes in cervical cancer
He M, Wang Y, Zhang G, Cao K, Yang M, Liu H
Journal of Gynecologic Oncology 2021;32(3)
Journal of Gynecologic Oncology 2021;32(3)
Relationship between immune checkpoint proteins, tumour microenvironment characteristics, and prognosis in primary operable colorectal cancer.
Al-Badran SS, Grant L, Campo MV, Inthagard J, Pennel K, Quinn J, Konanahalli P, Hayman L, Horgan PG, McMillan DC, Roxburgh CS, Roseweir A, Park JH, Edwards J
The journal of pathology. Clinical research 2021 Mar;7(2):121-134
The journal of pathology. Clinical research 2021 Mar;7(2):121-134
Clinicopathologic correlates of MYD88 L265P mutation and programmed cell death (PD-1) pathway in primary central nervous system lymphoma
Sethi T, Kovach A, Grover N, Huang L, Lee L, Rubinstein S, Wang Y, Morgan D, Greer J, Park S, Ann Thompson-Arildsen M, Yenamandra A, Vnencak-Jones C, Reddy N
Leukemia & Lymphoma 2019;60(12):2880-2889
Leukemia & Lymphoma 2019;60(12):2880-2889
A case report of clonal EBV-like memory CD4+ T cell activation in fatal checkpoint inhibitor-induced encephalitis
Johnson D, McDonnell W, Gonzalez-Ericsson P, Al-Rohil R, Mobley B, Salem J, Wang D, Sanchez V, Wang Y, Chastain C, Barker K, Liang Y, Warren S, Beechem J, Menzies A, Tio M, Long G, Cohen J, Guidon A, O’Hare M, Chandra S, Chowdhary A, Lebrun-Vignes B, Goldinger S, Rushing E, Buchbinder E, Mallal S, Shi C, Xu Y, Moslehi J, Sanders M, Sosman J, Balko J
Nature Medicine 2019;25(8):1243-1250
Nature Medicine 2019;25(8):1243-1250
CTLA-4+PD-1− Memory CD4+ T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques
McGary C, Deleage C, Harper J, Micci L, Ribeiro S, Paganini S, Kuri-Cervantes L, Benne C, Ryan E, Balderas R, Jean S, Easley K, Marconi V, Silvestri G, Estes J, Sekaly R, Paiardini M
Immunity 2017;47(4):776-788.e5
Immunity 2017;47(4):776-788.e5
PD-L1 expression and its relationship with oncogenic drivers in non-small cell lung cancer (NSCLC).
Jiang L, Su X, Zhang T, Yin X, Zhang M, Fu H, Han H, Sun Y, Dong L, Qian J, Xu Y, Fu X, Gavine PR, Zhou Y, Tian K, Huang J, Shen D, Jiang H, Yao Y, Han B, Gu Y
Oncotarget 2017 Apr 18;8(16):26845-26857
Oncotarget 2017 Apr 18;8(16):26845-26857
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Recombinant expression validation
- Main image
- Experimental details
- Western blot analysis in control (vector only transfected HEK293T lysate) and pDCD1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY401555).
- Sample type
- Human
- Protocol
- Protocol
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human lymph node and liver tissues using HPA035981 antibody. Corresponding PDCD1 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
