Antibody data
- Antibody Data
- Antigen structure
- References [26]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 13205-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13205-1-AP, RRID:AB_2180306
- Product name
- RORC antibody
- Antibody type
- Polyclonal
- Description
- RORC antibody (Cat. #13205-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Sarcandra glabra (Thunb.) Nakai alleviates DSS-induced ulcerative colitis by promoting restitution, restoring barrier function, and modulating IL-17/Notch1/FoxP3 pathway in intestinal cells.
Kuijieling decoction regulates the Treg/Th17 cell balance in ulcerative colitis through the RA/RARα signaling pathway.
Aryl hydrocarbon receptors improve migraine-like pain behaviors in rats through the regulation of regulatory T cell/T-helper 17 cell-related homeostasis.
Fermented cordyceps powder alleviates silica-induced pulmonary inflammation and fibrosis in rats by regulating the Th immune response.
Effects of lactate on metabolism and differentiation of CD4(+)T cells.
Liangxue Jiedu formula improves imiquimod-induced psoriasiform dermatitis with circadian desynchrony by regulating Th17 cell differentiation based on network pharmacological analysis.
Immuno-Responsive Gene-1: A mitochondrial gene regulates pathogenic Th17 in CNS autoimmunity mouse model.
Ryanodine receptor 2 promotes colorectal cancer metastasis by the ROS/BACH1 axis.
Dietary glutamate enhances intestinal immunity by modulating microbiota and Th17/Treg balance-related immune signaling in piglets after lipopolysaccharide challenge.
Analysis of the potential association between ferroptosis and immune in hepatocellular carcinoma and their relationship with prognosis.
Folic acid intervention changes liver Foxp3 methylation and ameliorates the damage caused by Th17/Treg imbalance after long-term alcohol exposure.
Extracts of Poria cocos improve functional dyspepsia via regulating brain-gut peptides, immunity and repairing of gastrointestinal mucosa.
Targeting the cholesterol-RORα/γ axis inhibits colorectal cancer progression through degrading c-myc.
Qing-Chang-Hua-Shi granule ameliorates DSS-induced colitis by activating NLRP6 signaling and regulating Th17/Treg balance.
Huganbuzure Granule Attenuates Concanavalin-A-Induced Immune Liver Injury in Mice via Regulating the Balance of Th1/Th2/Th17/Treg Cells and Inhibiting Apoptosis.
Interference with the expression of S1PR1 or STAT3 attenuates valvular damage due to rheumatic heart disease.
Melatonin mediates monochromatic light-induced proliferation of T/B lymphocytes in the spleen via the membrane receptor or nuclear receptor.
Baicalin suppresses Th1 and Th17 responses and promotes Treg response to ameliorate sepsis-associated pancreatic injury via the RhoA-ROCK pathway.
The Chinese medicinal herb decoction QRZSLXF enhances anti-inflammatory effect in TNBS-induced colitis via balancing Th17/Tregs differentiation.
Retinoic Acid-Related Orphan Receptor C Regulates Proliferation, Glycolysis, and Chemoresistance via the PD-L1/ITGB6/STAT3 Signaling Axis in Bladder Cancer.
Bronchial epithelial cells of young and old mice directly regulate the differentiation of Th2 and Th17.
Erythropoietin Treatment Ameliorates Lupus Nephritis of MRL/lpr Mice.
Yu Gan Long reduces rat liver fibrosis by blocking TGF-β1/Smad pathway and modulating the immunity.
Glucocorticoid-induced leucine zipper overexpression inhibits lipopolysaccharide-induced retinal inflammation in rats.
Upregulated Expression of microRNA-16 Correlates with Th17/Treg Cell Imbalance in Patients with Rheumatoid Arthritis.
Effect of IL-17 in the development of colon cancer in mice.
Zhang S, Li Y, Chen G, Wang X, Wu B
Journal of ethnopharmacology 2024 Jun 28;328:118131
Journal of ethnopharmacology 2024 Jun 28;328:118131
Kuijieling decoction regulates the Treg/Th17 cell balance in ulcerative colitis through the RA/RARα signaling pathway.
Xiao S, Yan Y, Shao M, Zhou X, Niu Z, Wu Y, Li Y, Cui Y, Long Y, Du Q
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116909
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116909
Aryl hydrocarbon receptors improve migraine-like pain behaviors in rats through the regulation of regulatory T cell/T-helper 17 cell-related homeostasis.
Yang L, Zhou Y, Zhang L, Wang Y, Zhang Y, Xiao Z
Headache 2023 Sep;63(8):1045-1060
Headache 2023 Sep;63(8):1045-1060
Fermented cordyceps powder alleviates silica-induced pulmonary inflammation and fibrosis in rats by regulating the Th immune response.
Pu S, Yang Z, Zhang X, Li M, Han N, Yang X, He J, Yu G, Meng X, Jia Q, Shao H
Chinese medicine 2023 Oct 12;18(1):131
Chinese medicine 2023 Oct 12;18(1):131
Effects of lactate on metabolism and differentiation of CD4(+)T cells.
Zhang YT, Xing ML, Fang HH, Li WD, Wu L, Chen ZP
Molecular immunology 2023 Feb;154:96-107
Molecular immunology 2023 Feb;154:96-107
Liangxue Jiedu formula improves imiquimod-induced psoriasiform dermatitis with circadian desynchrony by regulating Th17 cell differentiation based on network pharmacological analysis.
Xie X, Zhang L, Lin Y, Liu X, Han X, Li P
Journal of ethnopharmacology 2023 Dec 5;317:116807
Journal of ethnopharmacology 2023 Dec 5;317:116807
Immuno-Responsive Gene-1: A mitochondrial gene regulates pathogenic Th17 in CNS autoimmunity mouse model.
Nematullah M, Fatma M, Rashid F, Ayasolla K, Ahmed ME, Mir S, Zahoor I, Rattan R, Giri S
bioRxiv : the preprint server for biology 2023 Dec 25;
bioRxiv : the preprint server for biology 2023 Dec 25;
Ryanodine receptor 2 promotes colorectal cancer metastasis by the ROS/BACH1 axis.
Chen T, Zhang X, Ding X, Feng J, Zhang X, Xie D, Wang X
Molecular oncology 2023 Apr;17(4):695-709
Molecular oncology 2023 Apr;17(4):695-709
Dietary glutamate enhances intestinal immunity by modulating microbiota and Th17/Treg balance-related immune signaling in piglets after lipopolysaccharide challenge.
Liu G, Gu K, Liu X, Jia G, Zhao H, Chen X, Wang J
Food research international (Ottawa, Ont.) 2023 Apr;166:112597
Food research international (Ottawa, Ont.) 2023 Apr;166:112597
Analysis of the potential association between ferroptosis and immune in hepatocellular carcinoma and their relationship with prognosis.
Wen K, Yang F, Hu L, Shi J, Mui S, Wang W, Liao H, Li H, Xiao Z, Yan Y
Frontiers in oncology 2022;12:1031156
Frontiers in oncology 2022;12:1031156
Folic acid intervention changes liver Foxp3 methylation and ameliorates the damage caused by Th17/Treg imbalance after long-term alcohol exposure.
Zhao H, Guo P, Zuo Y, Wang Y, Zhao H, Lan T, Xue M, Zhang H, Liang H
Food & function 2022 May 10;13(9):5262-5274
Food & function 2022 May 10;13(9):5262-5274
Extracts of Poria cocos improve functional dyspepsia via regulating brain-gut peptides, immunity and repairing of gastrointestinal mucosa.
Tu Y, Luo X, Liu D, Li H, Xia H, Ma C, Zhang D, Yang Y, Pan X, Wang T, Xia Y, Dan H, You P, Ye X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153875
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153875
Targeting the cholesterol-RORα/γ axis inhibits colorectal cancer progression through degrading c-myc.
Wang YN, Ruan DY, Wang ZX, Yu K, Rong DL, Liu ZX, Wang F, Hu JJ, Jin Y, Wu QN, Pu HY, Wang M, Xu RH, Zeng ZL
Oncogene 2022 Dec;41(49):5266-5278
Oncogene 2022 Dec;41(49):5266-5278
Qing-Chang-Hua-Shi granule ameliorates DSS-induced colitis by activating NLRP6 signaling and regulating Th17/Treg balance.
Cheng C, Hu J, Li Y, Ji Y, Lian Z, Au R, Xu F, Li W, Shen H, Zhu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Dec;107:154452
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Dec;107:154452
Huganbuzure Granule Attenuates Concanavalin-A-Induced Immune Liver Injury in Mice via Regulating the Balance of Th1/Th2/Th17/Treg Cells and Inhibiting Apoptosis.
Wang M, Yin H, Xia Y, Tu Y, Zou X, Song W, Luo L, Wu H, Yang Y, Zan J, Liu Y, Dan H, Yin Q, You P
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5578021
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5578021
Interference with the expression of S1PR1 or STAT3 attenuates valvular damage due to rheumatic heart disease.
Xian S, Chen A, Wu Y, Wen H, Lu C, Huang F, Zeng Z
International journal of molecular medicine 2021 Sep;48(3)
International journal of molecular medicine 2021 Sep;48(3)
Melatonin mediates monochromatic light-induced proliferation of T/B lymphocytes in the spleen via the membrane receptor or nuclear receptor.
Xiong J, Wang Z, Cao J, Dong Y, Chen Y
Poultry science 2020 Sep;99(9):4294-4302
Poultry science 2020 Sep;99(9):4294-4302
Baicalin suppresses Th1 and Th17 responses and promotes Treg response to ameliorate sepsis-associated pancreatic injury via the RhoA-ROCK pathway.
Liu P, Xiao Z, Yan H, Lu X, Zhang X, Luo L, Long C, Zhu Y
International immunopharmacology 2020 Sep;86:106685
International immunopharmacology 2020 Sep;86:106685
The Chinese medicinal herb decoction QRZSLXF enhances anti-inflammatory effect in TNBS-induced colitis via balancing Th17/Tregs differentiation.
Zhang M, Fan H, Tan S, Tang Q, Liu X, Zuo D, Liao Y, Nan Z, Tan C
Journal of ethnopharmacology 2020 Apr 6;251:112549
Journal of ethnopharmacology 2020 Apr 6;251:112549
Retinoic Acid-Related Orphan Receptor C Regulates Proliferation, Glycolysis, and Chemoresistance via the PD-L1/ITGB6/STAT3 Signaling Axis in Bladder Cancer.
Cao D, Qi Z, Pang Y, Li H, Xie H, Wu J, Huang Y, Zhu Y, Shen Y, Zhu Y, Dai B, Hu X, Ye D, Wang Z
Cancer research 2019 May 15;79(10):2604-2618
Cancer research 2019 May 15;79(10):2604-2618
Bronchial epithelial cells of young and old mice directly regulate the differentiation of Th2 and Th17.
Liu D, He L, Ding N, Sun W, Qiu L, Xu L, Jia A, Peng C, Zhang D, Xiang X
Bioscience reports 2019 Feb 28;39(2)
Bioscience reports 2019 Feb 28;39(2)
Erythropoietin Treatment Ameliorates Lupus Nephritis of MRL/lpr Mice.
Zhang Z, Liu D, Zhang X, Wang X
Inflammation 2018 Oct;41(5):1888-1899
Inflammation 2018 Oct;41(5):1888-1899
Yu Gan Long reduces rat liver fibrosis by blocking TGF-β1/Smad pathway and modulating the immunity.
Xia Y, Yu B, Ma C, Tu Y, Zhai L, Yang Y, Liu D, Liu Y, Wu H, Dan H, You P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1332-1338
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1332-1338
Glucocorticoid-induced leucine zipper overexpression inhibits lipopolysaccharide-induced retinal inflammation in rats.
Gu R, Lei B, Shu Q, Li G, Xu G
Experimental eye research 2017 Dec;165:151-163
Experimental eye research 2017 Dec;165:151-163
Upregulated Expression of microRNA-16 Correlates with Th17/Treg Cell Imbalance in Patients with Rheumatoid Arthritis.
Wu YH, Liu W, Xue B, Zhang L, Liu XY, Liu B, Wang Y, Cai Y, Duan R
DNA and cell biology 2016 Dec;35(12):853-860
DNA and cell biology 2016 Dec;35(12):853-860
Effect of IL-17 in the development of colon cancer in mice.
Yang L, Liu H, Zhang L, Hu J, Chen H, Wang L, Yin X, Li Q, Qi Y
Oncology letters 2016 Dec;12(6):4929-4936
Oncology letters 2016 Dec;12(6):4929-4936
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RORC antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RORC. This antibody recognizes human, mouse, rat antigen. The RORC antibody has been validated for the following applications: ELISA, WB analysis.