55439-1-AP

antibody from Proteintech Group

Targeting: LORICRIN LOR

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

55439-1-AP

Provider

Proteintech Group

Product name

Loricrin antibody

Antibody type

Polyclonal

Description

Loricrin antibody (Cat. #55439-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB, ELISA.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

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Biochemistry and biophysics reports 2026 Mar;45:102409

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Dual-Targeting Oligopeptide-215 Regulates Skin Barrier Homeostasis Through Concurrent Modulation of JAK-STAT and NF-κB Signaling.

Zhang Q, Hu C, Chen Y, Chen Y, Guo C, Liu Z, Ding W
Journal of cosmetic dermatology 2026 Mar;25(3):e70704

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DAPK1 orchestrates cell division and junction to control corneal epithelial development.

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European journal of cell biology 2026 Jun;105(2):151532

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Rutin targets PD-L1 for the treatment of atopic dermatitis: network pharmacological analysis and experimental evidence.

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NOD2-Induced IκBζ Mediates a Protective Host Response against Epicutaneous Staphylococcus aureus Infection.

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Targeting mitochondrial dysfunction in atopic dermatitis with trilinolein: A triacylglycerol from the medicinal plant Cannabis fructus.

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Topical application of Artemisia annua L. essential oil ameliorates 2,4-dintrochlorobenzene-induced atopic dermatitis in mice.

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Journal of ethnopharmacology 2024 Oct 28;333:118439

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Foods (Basel, Switzerland) 2024 Dec 5;13(23)

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Epidermal keratinocyte-specific STAT3 deficiency aggravated atopic dermatitis-like skin inflammation in mice through TSLP upregulation.

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Frontiers in immunology 2023;14:1273182

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GDU-952, a novel AhR agonist ameliorates skin barrier abnormalities and immune dysfunction in DNFB-induced atopic dermatitis in mice.

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Biochemical pharmacology 2023 Nov;217:115835

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Androgenic induction of penile features in postnatal female mouse external genitalia from birth to adulthood: Is the female sexual phenotype ever irreversibly determined?

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Pyridoxine Has a Potential to Prevent the Appearance of Pigmented Spots: Effects on the Phagocytosis and Differentiation of Keratinocytes.

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ENKD1 promotes epidermal stratification by regulating spindle orientation in basal keratinocytes.

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Skin chronological aging drives age-related bone loss via secretion of cystatin-A.

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KDF1 Novel Variant Causes Unique Dental and Oral Epithelial Defects.

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International journal of molecular sciences 2022 Oct 18;23(20)

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Inhibiting Hyper-O-GlcNAcylation of c-Myc accelerate diabetic wound healing by alleviating keratinocyte dysfunction.

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Burns & trauma 2021;9:tkab031

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c-Myc Upregulated by High Glucose Inhibits HaCaT Differentiation by S100A6 Transcriptional Activation.

Zhang J, Yang P, Liu D, Gao M, Wang J, Wang X, Liu Y, Zhang X
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Cystatin-B Negatively Regulates the Malignant Characteristics of Oral Squamous Cell Carcinoma Possibly Via the Epithelium Proliferation/Differentiation Program.

Xu TT, Zeng XW, Wang XH, Yang LX, Luo G, Yu T
Frontiers in oncology 2021;11:707066

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Cornification and classical versus nonclassical androgen receptor signaling in mouse penile/preputial development.

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Differentiation; research in biological diversity 2021 Sep-Oct;121:1-12

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Journal of the European Academy of Dermatology and Venereology : JEADV 2021 Jun;35(6):1393-1406

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Oat β-glucan ameliorates epidermal barrier disruption by upregulating the expression of CaSR through dectin-1-mediated ERK and p38 signaling pathways.

Gao S, Chen Y, Zhao J, Jing R, Guo K, Wang L, Li X, Li C, Hu Z, Xu N
International journal of biological macromolecules 2021 Aug 31;185:876-889

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Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.

Li Y, Tang L, Yue J, Gou X, Lin A, Weatherbee SD, Wu X
EMBO reports 2020 May 6;21(5):e48566

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Poncirus Trifoliata (L.) Raf. Extract Inhibits the Development of Atopic Dermatitis-like Lesions in Human Keratinocytes and NC/Nga mice.

Cha KJ, Kashif A, Hong MH, Kim G, Lee JS, Kim IS
International journal of medical sciences 2019;16(8):1116-1122

---

Chaenomeles sinensis Koehne extract suppresses the development of atopic dermatitis-like lesions by regulating cytokine and filaggrin expression in NC/Nga mice.

Cha KJ, Song CS, Lee JS, Kashif A, Hong MH, Kim G, Kim IS
International journal of medical sciences 2019;16(12):1604-1613

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

A431 cells were subjected to SDS PAGE followed by western blot with 55439-1-AP(LOR antibody) at dilution of 1:500

Sample type

cell line

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

The Loricrin antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human Loricrin. This antibody recognizes human, mouse antigen. The Loricrin antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.

Appendix

55439-1-AP.pdf

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