Antibody data
- Antibody Data
- Antigen structure
- References [20]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 55439-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- Loricrin antibody
- Antibody type
- Polyclonal
- Description
- Loricrin antibody (Cat. #55439-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Denticleless E3 ubiquitin protein ligase (DTL) maintains the proliferation and differentiation of epidermis and hair follicles during skin development.
The m(6) A modification of Il17a in CD4(+) T cells promotes inflammation in psoriasis.
Epidermal keratinocyte-specific STAT3 deficiency aggravated atopic dermatitis-like skin inflammation in mice through TSLP upregulation.
GDU-952, a novel AhR agonist ameliorates skin barrier abnormalities and immune dysfunction in DNFB-induced atopic dermatitis in mice.
Androgenic induction of penile features in postnatal female mouse external genitalia from birth to adulthood: Is the female sexual phenotype ever irreversibly determined?
Pyridoxine Has a Potential to Prevent the Appearance of Pigmented Spots: Effects on the Phagocytosis and Differentiation of Keratinocytes.
ENKD1 promotes epidermal stratification by regulating spindle orientation in basal keratinocytes.
Skin chronological aging drives age-related bone loss via secretion of cystatin-A.
KDF1 Novel Variant Causes Unique Dental and Oral Epithelial Defects.
FGF21 promotes migration and differentiation of epidermal cells during wound healing via SIRT1-dependent autophagy.
Exosomes from human induced pluripotent stem cells-derived keratinocytes accelerate burn wound healing through miR-762 mediated promotion of keratinocytes and endothelial cells migration.
Inhibiting Hyper-O-GlcNAcylation of c-Myc accelerate diabetic wound healing by alleviating keratinocyte dysfunction.
c-Myc Upregulated by High Glucose Inhibits HaCaT Differentiation by S100A6 Transcriptional Activation.
Cystatin-B Negatively Regulates the Malignant Characteristics of Oral Squamous Cell Carcinoma Possibly Via the Epithelium Proliferation/Differentiation Program.
Cornification and classical versus nonclassical androgen receptor signaling in mouse penile/preputial development.
Differentially expressed proteins identified by TMT proteomics analysis in children with verrucous epidermal naevi.
Oat β-glucan ameliorates epidermal barrier disruption by upregulating the expression of CaSR through dectin-1-mediated ERK and p38 signaling pathways.
Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.
Poncirus Trifoliata (L.) Raf. Extract Inhibits the Development of Atopic Dermatitis-like Lesions in Human Keratinocytes and NC/Nga mice.
Chaenomeles sinensis Koehne extract suppresses the development of atopic dermatitis-like lesions by regulating cytokine and filaggrin expression in NC/Nga mice.
Lin Y, Tang W, Huang P, Wang Z, Duan L, Jia C, Sun R, Liu L, Shen J
Developmental dynamics : an official publication of the American Association of Anatomists 2024 Jul;253(7):635-647
Developmental dynamics : an official publication of the American Association of Anatomists 2024 Jul;253(7):635-647
The m(6) A modification of Il17a in CD4(+) T cells promotes inflammation in psoriasis.
Yuan L, Chen S, Ding K, Wang X, Lv W, Liu Y, He S, Yu Y, Yang B, Huang T
Experimental dermatology 2024 Jan;33(1):e14879
Experimental dermatology 2024 Jan;33(1):e14879
Epidermal keratinocyte-specific STAT3 deficiency aggravated atopic dermatitis-like skin inflammation in mice through TSLP upregulation.
Wang ZY, Zheng YX, Xu F, Cui YZ, Chen XY, Chen SQ, Yan BX, Zhou Y, Zheng M, Man XY
Frontiers in immunology 2023;14:1273182
Frontiers in immunology 2023;14:1273182
GDU-952, a novel AhR agonist ameliorates skin barrier abnormalities and immune dysfunction in DNFB-induced atopic dermatitis in mice.
Liang YH, Shu P, Li YL, Li M, Ye ZH, Chu S, Du ZY, Dong CZ, Meunier B, Chen HX
Biochemical pharmacology 2023 Nov;217:115835
Biochemical pharmacology 2023 Nov;217:115835
Androgenic induction of penile features in postnatal female mouse external genitalia from birth to adulthood: Is the female sexual phenotype ever irreversibly determined?
Cunha GR, Cao M, Derpinghaus A, Baskin LS
Differentiation; research in biological diversity 2023 May-Jun;131:1-26
Differentiation; research in biological diversity 2023 May-Jun;131:1-26
Pyridoxine Has a Potential to Prevent the Appearance of Pigmented Spots: Effects on the Phagocytosis and Differentiation of Keratinocytes.
Katsuyama Y, Hiyama K, Sawamura A, Kawase I, Okano Y, Masaki H
Biological & pharmaceutical bulletin 2022;45(9):1378-1384
Biological & pharmaceutical bulletin 2022;45(9):1378-1384
ENKD1 promotes epidermal stratification by regulating spindle orientation in basal keratinocytes.
Zhong T, Wu X, Xie W, Luo X, Song T, Sun S, Luo Y, Li D, Liu M, Xie S, Zhou J
Cell death and differentiation 2022 Sep;29(9):1719-1729
Cell death and differentiation 2022 Sep;29(9):1719-1729
Skin chronological aging drives age-related bone loss via secretion of cystatin-A.
Liang W, Chen Q, Cheng S, Wei R, Li Y, Yao C, Ouyang Z, Kang D, Chen A, Liu Z, Li K, Bai X, Li Q, Huang B
Nature aging 2022 Oct;2(10):906-922
Nature aging 2022 Oct;2(10):906-922
KDF1 Novel Variant Causes Unique Dental and Oral Epithelial Defects.
Yu M, Liu H, Liu Y, Zheng J, Wu J, Sun K, Feng H, Liu H, Han D
International journal of molecular sciences 2022 Oct 18;23(20)
International journal of molecular sciences 2022 Oct 18;23(20)
FGF21 promotes migration and differentiation of epidermal cells during wound healing via SIRT1-dependent autophagy.
Chen X, Tong G, Fan J, Shen Y, Wang N, Gong W, Hu Z, Zhu K, Li X, Jin L, Cong W, Xiao J, Zhu Z
British journal of pharmacology 2022 Mar;179(5):1102-1121
British journal of pharmacology 2022 Mar;179(5):1102-1121
Exosomes from human induced pluripotent stem cells-derived keratinocytes accelerate burn wound healing through miR-762 mediated promotion of keratinocytes and endothelial cells migration.
Bo Y, Yang L, Liu B, Tian G, Li C, Zhang L, Yan Y
Journal of nanobiotechnology 2022 Jun 21;20(1):291
Journal of nanobiotechnology 2022 Jun 21;20(1):291
Inhibiting Hyper-O-GlcNAcylation of c-Myc accelerate diabetic wound healing by alleviating keratinocyte dysfunction.
Zhang J, Yang P, Liu D, Gao M, Wang J, Yu T, Zhang X, Liu Y
Burns & trauma 2021;9:tkab031
Burns & trauma 2021;9:tkab031
c-Myc Upregulated by High Glucose Inhibits HaCaT Differentiation by S100A6 Transcriptional Activation.
Zhang J, Yang P, Liu D, Gao M, Wang J, Wang X, Liu Y, Zhang X
Frontiers in endocrinology 2021;12:676403
Frontiers in endocrinology 2021;12:676403
Cystatin-B Negatively Regulates the Malignant Characteristics of Oral Squamous Cell Carcinoma Possibly Via the Epithelium Proliferation/Differentiation Program.
Xu TT, Zeng XW, Wang XH, Yang LX, Luo G, Yu T
Frontiers in oncology 2021;11:707066
Frontiers in oncology 2021;11:707066
Cornification and classical versus nonclassical androgen receptor signaling in mouse penile/preputial development.
Cunha GR, Cao M, Derpinghaus A, Baskin LS, Cooke P, Walker W
Differentiation; research in biological diversity 2021 Sep-Oct;121:1-12
Differentiation; research in biological diversity 2021 Sep-Oct;121:1-12
Differentially expressed proteins identified by TMT proteomics analysis in children with verrucous epidermal naevi.
Yuan T, Cai ML, Sheng YM, Ding X, Shen TT, Li WR, Huang H, Liang B, Zhang XJ, Zhu QX
Journal of the European Academy of Dermatology and Venereology : JEADV 2021 Jun;35(6):1393-1406
Journal of the European Academy of Dermatology and Venereology : JEADV 2021 Jun;35(6):1393-1406
Oat β-glucan ameliorates epidermal barrier disruption by upregulating the expression of CaSR through dectin-1-mediated ERK and p38 signaling pathways.
Gao S, Chen Y, Zhao J, Jing R, Guo K, Wang L, Li X, Li C, Hu Z, Xu N
International journal of biological macromolecules 2021 Aug 31;185:876-889
International journal of biological macromolecules 2021 Aug 31;185:876-889
Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.
Li Y, Tang L, Yue J, Gou X, Lin A, Weatherbee SD, Wu X
EMBO reports 2020 May 6;21(5):e48566
EMBO reports 2020 May 6;21(5):e48566
Poncirus Trifoliata (L.) Raf. Extract Inhibits the Development of Atopic Dermatitis-like Lesions in Human Keratinocytes and NC/Nga mice.
Cha KJ, Kashif A, Hong MH, Kim G, Lee JS, Kim IS
International journal of medical sciences 2019;16(8):1116-1122
International journal of medical sciences 2019;16(8):1116-1122
Chaenomeles sinensis Koehne extract suppresses the development of atopic dermatitis-like lesions by regulating cytokine and filaggrin expression in NC/Nga mice.
Cha KJ, Song CS, Lee JS, Kashif A, Hong MH, Kim G, Kim IS
International journal of medical sciences 2019;16(12):1604-1613
International journal of medical sciences 2019;16(12):1604-1613
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A431 cells were subjected to SDS PAGE followed by western blot with 55439-1-AP(LOR antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Loricrin antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human Loricrin. This antibody recognizes human, mouse antigen. The Loricrin antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.