Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Flow cytometry [1]
- Other assay [1]
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Validation data
Reference
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- Product number
- AHR0061 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- IL-6 Receptor Monoclonal Antibody (B-R6)
- Antibody type
- Monoclonal
- Antigen
- Other
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- B-R6
- Vial size
- 100 µg
- Concentration
- 4.0 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references Salivary Gland Stem Cells Age Prematurely in Primary Sjögren's Syndrome.
Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2.
Involvement of hepcidin in the anemia of multiple myeloma.
Interferon alpha induces cell death through interference with interleukin 6 signaling and inhibition of STAT3 activity.
Retinoic acid inhibits IL-6-dependent but not constitutive STAT3 activation in Epstein-Barr virus-immortalized B lymphocytes.
Interleukin-6 enhances whereas tumor necrosis factor alpha and interferons inhibit integrin expression and adhesion of human mast cells to extracellular matrix proteins.
Shedding of the interleukin-6 (IL-6) receptor (gp80) determines the ability of IL-6 to induce gp130 phosphorylation in human osteoblasts.
Human herpesvirus 8-encoded interleukin 6 activates HIV-1 in the U1 monocytic cell line.
Human herpesvirus 8-encoded interleukin 6 activates HIV-1 in the U1 monocytic cell line.
Selective proteolytic cleavage of IL-2 receptor and IL-6 receptor ligand binding chains by neutrophil-derived serine proteases at foci of inflammation.
Pringle S, Wang X, Verstappen GMPJ, Terpstra JH, Zhang CK, He A, Patel V, Jones RE, Baird DM, Spijkervet FKL, Vissink A, Bootsma H, Coppes RP, Kroese FGM
Arthritis & rheumatology (Hoboken, N.J.) 2019 Jan;71(1):133-142
Arthritis & rheumatology (Hoboken, N.J.) 2019 Jan;71(1):133-142
Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2.
Blechacz BR, Smoot RL, Bronk SF, Werneburg NW, Sirica AE, Gores GJ
Hepatology (Baltimore, Md.) 2009 Dec;50(6):1861-70
Hepatology (Baltimore, Md.) 2009 Dec;50(6):1861-70
Involvement of hepcidin in the anemia of multiple myeloma.
Sharma S, Nemeth E, Chen YH, Goodnough J, Huston A, Roodman GD, Ganz T, Lichtenstein A
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Jun 1;14(11):3262-7
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Jun 1;14(11):3262-7
Interferon alpha induces cell death through interference with interleukin 6 signaling and inhibition of STAT3 activity.
Thyrell L, Arulampalam V, Hjortsberg L, Farnebo M, Grandér D, Pokrovskaja Tamm K
Experimental cell research 2007 Nov 15;313(19):4015-24
Experimental cell research 2007 Nov 15;313(19):4015-24
Retinoic acid inhibits IL-6-dependent but not constitutive STAT3 activation in Epstein-Barr virus-immortalized B lymphocytes.
Zancai P, Cariati R, Quaia M, Guidoboni M, Rizzo S, Boiocchi M, Dolcetti R
International journal of oncology 2004 Aug;25(2):345-55
International journal of oncology 2004 Aug;25(2):345-55
Interleukin-6 enhances whereas tumor necrosis factor alpha and interferons inhibit integrin expression and adhesion of human mast cells to extracellular matrix proteins.
Schoeler D, Grützkau A, Henz BM, Küchler J, Krüger-Krasagakis S
The Journal of investigative dermatology 2003 May;120(5):795-801
The Journal of investigative dermatology 2003 May;120(5):795-801
Shedding of the interleukin-6 (IL-6) receptor (gp80) determines the ability of IL-6 to induce gp130 phosphorylation in human osteoblasts.
Vermes C, Jacobs JJ, Zhang J, Firneisz G, Roebuck KA, Glant TT
The Journal of biological chemistry 2002 May 10;277(19):16879-87
The Journal of biological chemistry 2002 May 10;277(19):16879-87
Human herpesvirus 8-encoded interleukin 6 activates HIV-1 in the U1 monocytic cell line.
Gage JR, Breen EC, Echeverri A, Magpantay L, Kishimoto T, Miles S, Martínez-Maza O
AIDS (London, England) 1999 Oct 1;13(14):1851-5
AIDS (London, England) 1999 Oct 1;13(14):1851-5
Human herpesvirus 8-encoded interleukin 6 activates HIV-1 in the U1 monocytic cell line.
Gage JR, Breen EC, Echeverri A, Magpantay L, Kishimoto T, Miles S, Martínez-Maza O
AIDS (London, England) 1999 Oct 1;13(14):1851-5
AIDS (London, England) 1999 Oct 1;13(14):1851-5
Selective proteolytic cleavage of IL-2 receptor and IL-6 receptor ligand binding chains by neutrophil-derived serine proteases at foci of inflammation.
Bank U, Reinhold D, Schneemilch C, Kunz D, Synowitz HJ, Ansorge S
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1999 Nov;19(11):1277-87
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1999 Nov;19(11):1277-87
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Flow cytometry analysis using an IL-6 Receptor Monoclonal antibody, clone B-R6 (Product # AHR0061) in U266 cells.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL