Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
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- Product number
- MAB1830 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse IL-6R alpha Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects mouse IL-6 R alpha in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human IL-6 R alpha is observed.
- Reactivity
- Mouse
- Host
- Rat
- Conjugate
- Unconjugated
- Antigen sequence
P22272
- Isotype
- IgG
- Antibody clone number
- 255821
- Vial size
- 500 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Autocrine interleukin-6 drives skin-derived mesenchymal stem cell trafficking via regulating voltage-gated Ca(2+) channels.
Ifitm3 limits the severity of acute influenza in mice.
Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine model.
Ke F, Zhang L, Liu Z, Liu J, Yan S, Xu Z, Bai J, Zhu H, Lou F, Wang H, Shi Y, Jiang Y, Su B, Wang H
Stem cells (Dayton, Ohio) 2014 Oct;32(10):2799-810
Stem cells (Dayton, Ohio) 2014 Oct;32(10):2799-810
Ifitm3 limits the severity of acute influenza in mice.
Bailey CC, Huang IC, Kam C, Farzan M
PLoS pathogens 2012 Sep;8(9):e1002909
PLoS pathogens 2012 Sep;8(9):e1002909
Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine model.
Matsumoto S, Hara T, Mitsuyama K, Yamamoto M, Tsuruta O, Sata M, Scheller J, Rose-John S, Kado S, Takada T
Journal of immunology (Baltimore, Md. : 1950) 2010 Feb 1;184(3):1543-51
Journal of immunology (Baltimore, Md. : 1950) 2010 Feb 1;184(3):1543-51
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