MAB1830

antibody from R&D Systems

Targeting: IL6R CD126

Immunocytochemistry (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

MAB1830

Provider

R&D Systems

Product name

Mouse IL-6R alpha Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects mouse IL-6 R alpha in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human IL-6 R alpha is observed.

Reactivity

Mouse

Host

Rat

Conjugate

Unconjugated

Antigen sequence

P22272


Isotype

IgG

Antibody clone number

255821

Vial size

500 ug

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Autocrine interleukin-6 drives skin-derived mesenchymal stem cell trafficking via regulating voltage-gated Ca(2+) channels.

Ke F, Zhang L, Liu Z, Liu J, Yan S, Xu Z, Bai J, Zhu H, Lou F, Wang H, Shi Y, Jiang Y, Su B, Wang H
Stem cells (Dayton, Ohio) 2014 Oct;32(10):2799-810

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Ifitm3 limits the severity of acute influenza in mice.

Bailey CC, Huang IC, Kam C, Farzan M
PLoS pathogens 2012 Sep;8(9):e1002909

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Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine model.

Matsumoto S, Hara T, Mitsuyama K, Yamamoto M, Tsuruta O, Sata M, Scheller J, Rose-John S, Kado S, Takada T
Journal of immunology (Baltimore, Md. : 1950) 2010 Feb 1;184(3):1543-51