Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- ELISA [1]
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- Product number
- ABIN395681 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Interleukin-6 Receptor (IL6R) (AA 21-121) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 21-121
- Isotype
- IgG
- Antibody clone number
- 2G6
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Plasma soluble IL-6 receptor concentration in rheumatoid arthritis: associations with the rs8192284 IL6R polymorphism and with disease activity.
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).
Gene-gene interaction in regulatory T-cell function in atopy and asthma development in childhood.
Influence of IL6R rs8192284 polymorphism status in disease activity in rheumatoid arthritis.
Rodríguez-Rodríguez L, Lamas JR, Varadé J, López-Romero P, Tornero-Esteban P, Abasolo L, de la Concha EG, Jover JA, Urcelay E, Fernández-Gutiérrez B
Rheumatology international 2011 Mar;31(3):409-13
Rheumatology international 2011 Mar;31(3):409-13
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators.
Diabetes care 2010 Oct;33(10):2250-3
Diabetes care 2010 Oct;33(10):2250-3
A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).
Romero R, Friel LA, Velez Edwards DR, Kusanovic JP, Hassan SS, Mazaki-Tovi S, Vaisbuch E, Kim CJ, Erez O, Chaiworapongsa T, Pearce BD, Bartlett J, Salisbury BA, Anant MK, Vovis GF, Lee MS, Gomez R, Behnke E, Oyarzun E, Tromp G, Williams SM, Menon R
American journal of obstetrics and gynecology 2010 Oct;203(4):361.e1-361.e30
American journal of obstetrics and gynecology 2010 Oct;203(4):361.e1-361.e30
Gene-gene interaction in regulatory T-cell function in atopy and asthma development in childhood.
Bottema RW, Kerkhof M, Reijmerink NE, Thijs C, Smit HA, van Schayck CP, Brunekreef B, van Oosterhout AJ, Postma DS, Koppelman GH
The Journal of allergy and clinical immunology 2010 Aug;126(2):338-46, 346.e1-10
The Journal of allergy and clinical immunology 2010 Aug;126(2):338-46, 346.e1-10
Influence of IL6R rs8192284 polymorphism status in disease activity in rheumatoid arthritis.
Lamas JR, Rodríguez-Rodríguez L, Varadé J, López-Romero P, Tornero-Esteban P, Abasolo L, Urcelay E, Fernández-Gutiérrez B
The Journal of rheumatology 2010 Aug 1;37(8):1579-81
The Journal of rheumatology 2010 Aug 1;37(8):1579-81
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA