Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 23457-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- IL-6R antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated IL-6R antibody (Cat. #23457-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Prevention of IL-6 signaling ameliorates toluene diisocyanate-induced steroid-resistant asthma.
Chemerin promotes microangiopathy in diabetic retinopathy via activation of ChemR23 in rat primary microvascular endothelial cells.
Differential effects of EPA and DHA on DSS-induced colitis in mice and possible mechanisms involved.
Gelsolin Governs the Neuroendocrine Transdifferentiation of Prostate Cancer Cells and Suppresses the Apoptotic Machinery.
Upregulated MELK Leads to Doxorubicin Chemoresistance and M2 Macrophage Polarization via the miR-34a/JAK2/STAT3 Pathway in Uterine Leiomyosarcoma.
MiR-22 restrains proliferation of rheumatoid arthritis by targeting IL6R and may be concerned with the suppression of NF-κB pathway.
MicroRNA-34a deficiency leads to impaired wound closure by augmented inflammation in mice.
Human cancer cells suppress behaviors of endothelial progenitor cells through miR-21 targeting IL6R.
Inducible microRNA-590-5p inhibits host antiviral response by targeting the soluble interleukin-6 (IL6) receptor.
Death receptor 6 (DR6) is required for mouse B16 tumor angiogenesis via the NF-κB, P38 MAPK and STAT3 pathways.
Chen S, Chen Z, Deng Y, Zha S, Yu L, Li D, Liang Z, Yang K, Liu S, Chen R
Allergology international : official journal of the Japanese Society of Allergology 2022 Jan;71(1):73-82
Allergology international : official journal of the Japanese Society of Allergology 2022 Jan;71(1):73-82
Chemerin promotes microangiopathy in diabetic retinopathy via activation of ChemR23 in rat primary microvascular endothelial cells.
Jun L, Lin-Lin S, Hui S
Molecular vision 2021;27:575-587
Molecular vision 2021;27:575-587
Differential effects of EPA and DHA on DSS-induced colitis in mice and possible mechanisms involved.
Zhang Z, Xue Z, Yang H, Zhao F, Liu C, Chen J, Lu S, Zou Z, Zhou Y, Zhang X
Food & function 2021 Mar 1;12(4):1803-1817
Food & function 2021 Mar 1;12(4):1803-1817
Gelsolin Governs the Neuroendocrine Transdifferentiation of Prostate Cancer Cells and Suppresses the Apoptotic Machinery.
Oelrich F, Junker H, Stope MB, Erb HHH, Walther R, Venz S, Zimmermann U
Anticancer research 2021 Aug;41(8):3717-3729
Anticancer research 2021 Aug;41(8):3717-3729
Upregulated MELK Leads to Doxorubicin Chemoresistance and M2 Macrophage Polarization via the miR-34a/JAK2/STAT3 Pathway in Uterine Leiomyosarcoma.
Zhang Z, Sun C, Li C, Jiao X, Griffin BB, Dongol S, Wu H, Zhang C, Cao W, Dong R, Yang X, Zhang Q, Kong B
Frontiers in oncology 2020;10:453
Frontiers in oncology 2020;10:453
MiR-22 restrains proliferation of rheumatoid arthritis by targeting IL6R and may be concerned with the suppression of NF-κB pathway.
Yang QY, Yang KP, Li ZZ
The Kaohsiung journal of medical sciences 2020 Jan;36(1):20-26
The Kaohsiung journal of medical sciences 2020 Jan;36(1):20-26
MicroRNA-34a deficiency leads to impaired wound closure by augmented inflammation in mice.
Zhao N, Wang G, Long S, Hu M, Gao J, Ran X, Wang J, Su Y, Wang T
Annals of translational medicine 2020 Apr;8(7):447
Annals of translational medicine 2020 Apr;8(7):447
Human cancer cells suppress behaviors of endothelial progenitor cells through miR-21 targeting IL6R.
Wang W, Yuan X, Xu A, Zhu X, Zhan Y, Wang S, Liu M
Microvascular research 2018 Nov;120:21-28
Microvascular research 2018 Nov;120:21-28
Inducible microRNA-590-5p inhibits host antiviral response by targeting the soluble interleukin-6 (IL6) receptor.
Zhou Y, Xia Z, Cheng Z, Xu G, Yang X, Liu S, Zhu Y
The Journal of biological chemistry 2018 Nov 23;293(47):18168-18179
The Journal of biological chemistry 2018 Nov 23;293(47):18168-18179
Death receptor 6 (DR6) is required for mouse B16 tumor angiogenesis via the NF-κB, P38 MAPK and STAT3 pathways.
Yang X, Shi B, Li L, Xu Z, Ge Y, Shi J, Liu Y, Zheng D
Oncogenesis 2016 Mar 7;5:e206
Oncogenesis 2016 Mar 7;5:e206
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IL6R antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human IL6R. This antibody recognizes human, mouse antigen. The IL6R antibody has been validated for the following applications: ELISA, WB analysis.