ABIN155193

antibody from antibodies-online

Targeting: MFAP5 MAGP2, MP25

Western blot (Data presented on provider website)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN155193

Provider

antibodies-online

Product name

anti-Microfibrillar Associated Protein 5 (MFAP5) (C-Term) antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide corresponding to a region near the carboxy terminal end of human MAGP-2 protein. Remarks: Full length protein sequence for human MAGP-2 (173 aa, predicted MW 19.6 kDa): 1 msllgpkvll flaafiitsd wiplgvnsqr gddvtqatpe tftedpnlvn dpatdetvla 61 vladiapstd dlaslseknt taecwdekft ctrlysvhrp vkqcihqlcf tslrrmyivn 121 keicsrlvck eheamkdelc rqmaglpprr lrrsnyfrlp pcenvdlqrp ngl

Description

Immunoaffinity (from monospecific antiserum).

Reactivity

Human, Simian

Host

Rabbit

Epitope

C-Term

Vial size

0.1 mg

Concentration

0.95 mg/mL (by UV absorbance at 280 nm)

Storage

Store vial at 2-8°C prior to restoration. Restore with deionized water r equivalent, this antibody is stable for one month at 2-8°C as an undiluted liquid. For extended storage aliquot contents and freeze at -20°C or below. Centrifuge product if not completely clear after standing at room temperature.

Handling

Avoid repeated freezing and thawing. Dilute only prior to immediate use

References

Submitted references

The extracellular matrix protein MAGP-2 interacts with Jagged1 and induces its shedding from the cell surface.

Nehring LC, Miyamoto A, Hein PW, Weinmaster G, Shipley JM
The Journal of biological chemistry 2005 May 27;280(21):20349-55

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MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.

Hanssen E, Hew FH, Moore E, Gibson MA
The Journal of biological chemistry 2004 Jul 9;279(28):29185-94

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Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.

Penner AS, Rock MJ, Kielty CM, Shipley JM
The Journal of biological chemistry 2002 Sep 20;277(38):35044-9

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The exon structure of the human MAGP-2 gene. Similarity with the MAGP-1 gene is confined to two exons encoding a cysteine-rich region.

Hatzinikolas G, Gibson MA
The Journal of biological chemistry 1998 Nov 6;273(45):29309-14

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Further characterization of proteins associated with elastic fiber microfibrils including the molecular cloning of MAGP-2 (MP25)

Gibson MA, Hatzinikolas G, Kumaratilake JS, Sandberg LB, Nicholl JK, Sutherland GR, Cleary EG
The Journal of biological chemistry 1996 Jan 12;271(2):1096-103