abx016024

antibody from Abbexa

Targeting: ZBTB7B c-Krox, hcKrox, ZBTB15, ZFP67, ZNF857B

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

abx016024

Provider

Abbexa

Product name

Zinc Finger And BTB Domain-Containing Protein 7B (ZBTB7B) Antibody

Antibody type

Monoclonal

Description

ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors.It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment.Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively.ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes.It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Vial size

100 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.