Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 10278-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10278-1-AP, RRID:AB_2195624
- Product name
- TRAPB/SSR2 antibody
- Antibody type
- Polyclonal
- Description
- TRAPB/SSR2 antibody (Cat. #10278-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Eeyarestatin I (ESI)-induced ERAD inhibition exhibits anti-cancer activity through multiple mechanisms in human colorectal cancer cells.
Pleiotropic Function of Cellular Prion Protein: Encompassing Endoplasmic-Reticulum Stress, Cell Proliferation in Vascular Smooth Muscle Cells.
Knockdown of translocon-associated protein subunit beta (TRAPβ) stimulates cell cycle arrest and apoptosis in human colorectal cancer cells.
Signal recognition particle receptor-β (SR-β) coordinates cotranslational N-glycosylation.
Endoplasmic Reticulum Stress-Related Signature for Predicting Prognosis and Immune Features in Hepatocellular Carcinoma.
The Role of TRAPγ/SSR3 in Preproinsulin Translocation Into the Endoplasmic Reticulum.
Overexpression of SSR2 promotes proliferation of liver cancer cells and predicts prognosis of patients with hepatocellular carcinoma.
Deficient endoplasmic reticulum translocon-associated protein complex limits the biosynthesis of proinsulin and insulin.
The translocon-associated protein (TRAP) complex regulates quality control of N-linked glycosylation during ER stress.
Long noncoding RNA SNHG14 promotes hepatocellular carcinoma progression by regulating miR-876-5p/SSR2 axis.
RNF126-Mediated Reubiquitination Is Required for Proteasomal Degradation of p97-Extracted Membrane Proteins.
Peng J, Wei CI, Lee SH
European journal of pharmacology 2025 Jun 15;997:177623
European journal of pharmacology 2025 Jun 15;997:177623
Pleiotropic Function of Cellular Prion Protein: Encompassing Endoplasmic-Reticulum Stress, Cell Proliferation in Vascular Smooth Muscle Cells.
Bose R, Ghosh M, Ain R
Journal of cellular biochemistry 2025 Jan;126(1):e30692
Journal of cellular biochemistry 2025 Jan;126(1):e30692
Knockdown of translocon-associated protein subunit beta (TRAPβ) stimulates cell cycle arrest and apoptosis in human colorectal cancer cells.
Amarakoon D, Peng J, Wei CI, Lee SH
Biochimica et biophysica acta. Molecular cell research 2025 Dec;1872(8):120057
Biochimica et biophysica acta. Molecular cell research 2025 Dec;1872(8):120057
Signal recognition particle receptor-β (SR-β) coordinates cotranslational N-glycosylation.
Phoomak C, Rinis N, Baro M, Shrimal S, Bennett D, Shaffer SA, Lehrman M, Gilmore R, Contessa JN
Science advances 2023 Mar 17;9(11):eade8079
Science advances 2023 Mar 17;9(11):eade8079
Endoplasmic Reticulum Stress-Related Signature for Predicting Prognosis and Immune Features in Hepatocellular Carcinoma.
Zhang G, Sun J
Journal of immunology research 2022;2022:1366508
Journal of immunology research 2022;2022:1366508
The Role of TRAPγ/SSR3 in Preproinsulin Translocation Into the Endoplasmic Reticulum.
Xu X, Huang Y, Li X, Arvan P, Liu M
Diabetes 2022 Mar 1;71(3):440-452
Diabetes 2022 Mar 1;71(3):440-452
Overexpression of SSR2 promotes proliferation of liver cancer cells and predicts prognosis of patients with hepatocellular carcinoma.
Chen F, Chen, Wang J, Zhang S, Chen M, Zhang X, Wu Z
Journal of cellular and molecular medicine 2022 Jun;26(11):3169-3182
Journal of cellular and molecular medicine 2022 Jun;26(11):3169-3182
Deficient endoplasmic reticulum translocon-associated protein complex limits the biosynthesis of proinsulin and insulin.
Huang Y, Xu X, Arvan P, Liu M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21515
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21515
The translocon-associated protein (TRAP) complex regulates quality control of N-linked glycosylation during ER stress.
Phoomak C, Cui W, Hayman TJ, Yu SH, Zhao P, Wells L, Steet R, Contessa JN
Science advances 2021 Jan;7(3)
Science advances 2021 Jan;7(3)
Long noncoding RNA SNHG14 promotes hepatocellular carcinoma progression by regulating miR-876-5p/SSR2 axis.
Liao Z, Zhang H, Su C, Liu F, Liu Y, Song J, Zhu H, Fan Y, Zhang X, Dong W, Chen X, Liang H, Zhang B
Journal of experimental & clinical cancer research : CR 2021 Jan 23;40(1):36
Journal of experimental & clinical cancer research : CR 2021 Jan 23;40(1):36
RNF126-Mediated Reubiquitination Is Required for Proteasomal Degradation of p97-Extracted Membrane Proteins.
Hu X, Wang L, Wang Y, Ji J, Li J, Wang Z, Li C, Zhang Y, Zhang ZR
Molecular cell 2020 Jul 16;79(2):320-331.e9
Molecular cell 2020 Jul 16;79(2):320-331.e9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 10278-1-AP(TRAPB, SSR2 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 10278-1-AP(TRAPB, SSR2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The TRAPB/SSR2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TRAPB/SSR2. This antibody recognizes human,mouse,rat antigen. The TRAPB/SSR2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.