Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 24639-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- ISG20L2 antibody
- Antibody type
- Polyclonal
- Description
- ISG20L2 antibody (Cat. #24639-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Proteome-wide C-degron activity profiling connects conditional regulation of the CTLH E3 ligase complex to ribosome biogenesis.
The 3'-5' exoribonuclease ISG20L2 contributes to 3' terminus maturation of 18S and 28S ribosomal RNAs.
Molecular mechanism of human ISG20L2 for the ITS1 cleavage in the processing of 18S precursor ribosomal RNA.
ISG20L2 suppresses bortezomib antimyeloma activity by attenuating bortezomib binding to PSMB5.
Grant DW, Tan S, Ramage DE, Li MZ, Di Y, Tchasovnikarova IA, Weekes MP, Elledge SJ, Warren AJ, Timms RT
bioRxiv : the preprint server for biology 2026 Jan 14;
bioRxiv : the preprint server for biology 2026 Jan 14;
The 3'-5' exoribonuclease ISG20L2 contributes to 3' terminus maturation of 18S and 28S ribosomal RNAs.
Aubert M, Zuber H, Mommert-Tripon M, Page SL, Montel-Lehry N, Soldan V, Bosch S, Gagliardi D, Gleizes PE, O'Donohue MF
Nucleic acids research 2025 Nov 13;53(21)
Nucleic acids research 2025 Nov 13;53(21)
Molecular mechanism of human ISG20L2 for the ITS1 cleavage in the processing of 18S precursor ribosomal RNA.
Ma Y, Wang J, He X, Liu Y, Zhen S, An L, Yang Q, Niu F, Wang H, An B, Tai X, Yan Z, Wu C, Yang X, Liu X
Nucleic acids research 2024 Feb 28;52(4):1878-1895
Nucleic acids research 2024 Feb 28;52(4):1878-1895
ISG20L2 suppresses bortezomib antimyeloma activity by attenuating bortezomib binding to PSMB5.
Yang Y, Gao Y, Huang J, Yang Z, Luo H, Wang F, Xu J, Cui Y, Ding H, Lin Z, Zhai X, Qu Y, Zhang L, Liu T, Ye L, Niu T, Zheng Y
JCI insight 2022 Oct 10;7(19)
JCI insight 2022 Oct 10;7(19)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The ISG20L2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ISG20L2. This antibody recognizes human antigen. The ISG20L2 antibody has been validated for the following applications: ELISA, WB analysis.