AMM00183G

CD1B antibody from Leading Biology
CD1
Western blot
Recommended by provider
Immunocytochemistry
Recommended by provider
Immunoprecipitation
Recommended by provider
Immunohistochemistry
Recommended by provider
Flow cytometry
Recommended by provider

Antibody data

Product number
AMM00183G
Provider
Leading Biology
Product name
CD1b (T-Cell Surface Glycoprotein) Antibody - With BSA and Azide
Provider product page
Leading Biology - AMM00183G
Antibody type
Monoclonal
Description
The mouse monoclonal antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
RIV12
Storage
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Provider Type Product Number
- No reagents -