AMM00443G

CD1B antibody from Leading Biology
CD1
Immunocytochemistry
Recommended by provider
Flow cytometry
Recommended by provider

Antibody data

Product number
AMM00443G
Provider
Leading Biology
Product name
CD1b (T-Cell Surface Glycoprotein) Antibody - Without BSA and Azide
Provider product page
Leading Biology - AMM00443G
Antibody type
Monoclonal
Description
The mouse monoclonal antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.
Reactivity
Human
Host
Mouse
Antibody clone number
RIV12
Storage
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Provider Type Product Number
- No reagents -