Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- MAB7943 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB7943, RRID:AB_10677594
- Product name
- FCER1A monoclonal antibody, clone CRA1
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against recombinant FCER1A.
- Isotype
- IgG
- Antibody clone number
- CRA1
- Storage
- Store at -20°C. Aliquot to avoid repeated freezing and thawing.
Submitted references IgE- and FcepsilonRI-mediated migration of human basophils.
IgE enhances Fc epsilon receptor I expression and IgE-dependent release of histamine and lipid mediators from human umbilical cord blood-derived mast cells: synergistic effect of IL-4 and IgE on human mast cell Fc epsilon receptor I expression and mediator release.
The alpha subunit of the human IgE receptor (FcERI) is sufficient for high affinity IgE binding.
Suzukawa M, Hirai K, Iikura M, Nagase H, Komiya A, Yoshimura-Uchiyama C, Yamada H, Ra C, Ohta K, Yamamoto K, Yamaguchi M
International immunology 2005 Sep;17(9):1249-55
International immunology 2005 Sep;17(9):1249-55
IgE enhances Fc epsilon receptor I expression and IgE-dependent release of histamine and lipid mediators from human umbilical cord blood-derived mast cells: synergistic effect of IL-4 and IgE on human mast cell Fc epsilon receptor I expression and mediator release.
Yamaguchi M, Sayama K, Yano K, Lantz CS, Noben-Trauth N, Ra C, Costa JJ, Galli SJ
Journal of immunology (Baltimore, Md. : 1950) 1999 May 1;162(9):5455-65
Journal of immunology (Baltimore, Md. : 1950) 1999 May 1;162(9):5455-65
The alpha subunit of the human IgE receptor (FcERI) is sufficient for high affinity IgE binding.
Hakimi J, Seals C, Kondas JA, Pettine L, Danho W, Kochan J
The Journal of biological chemistry 1990 Dec 25;265(36):22079-81
The Journal of biological chemistry 1990 Dec 25;265(36):22079-81
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- FACS analysis of Chinese hamster ovary (CHO) transfectant cells expressing FCER1A (1 X 105) with FCER1A monoclonal antibody, clone CRA1 (Cat # MAB7943) and CRA2 antibodies by Indirect-immunostaining, using FITC-labeled secondary antibody.
- Validation comment
- Flow Cytometry