Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-L3178 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Mouse Anti-Human Fc epsilon RI alpha monoclonal antibody, clone 884815
- Antibody type
- Monoclonal
- Description
- The alpha subunit of the high affinity IgE receptor (Fc epsilon RI alpha or Fc epsilon RIA) is an IgE?binding type I transmembrane glycoprotein of the multichain immune recognition (MIRR) family. The receptor, Fc epsilon RI, is a tetrameric complex of one alpha, one beta and two gamma subunits ( alpha beta gamma 2) on mast cells and basophils. An alternate trimeric form ( alpha gamma 2) is expressed on human, but not rodent, mast cells, basophils, eosinophils and professional antigen presenting cells. While the gamma subunit is essential for expression of Fc epsilon RI alpha on the cell surface and for cell signaling, the beta subunit, when present, increases the halflife of the Fc epsilon RI complex on the cell surface
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 884815
- Vial size
- 100 ug
- Storage
- Long time storage is recommended at -20°C.
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