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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB2804 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2804, RRID:AB_1580040
- Product name
- STK11 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of STK11.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references An efficient expression system for the production of functionally active human LKB1.
IGF-1 phosphorylates AMPK-alpha subunit in ATM-dependent and LKB1-independent manner.
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.
Martínez-Torrecuadrada JL, Romero S, Núñez A, Alfonso P, Sánchez-Céspedes M, Casal JI
Journal of biotechnology 2005 Jan 12;115(1):23-34
Journal of biotechnology 2005 Jan 12;115(1):23-34
IGF-1 phosphorylates AMPK-alpha subunit in ATM-dependent and LKB1-independent manner.
Suzuki A, Kusakai G, Kishimoto A, Shimojo Y, Ogura T, Lavin MF, Esumi H
Biochemical and biophysical research communications 2004 Nov 19;324(3):986-92
Biochemical and biophysical research communications 2004 Nov 19;324(3):986-92
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.
Shaw RJ, Kosmatka M, Bardeesy N, Hurley RL, Witters LA, DePinho RA, Cantley LC
Proceedings of the National Academy of Sciences of the United States of America 2004 Mar 9;101(10):3329-35
Proceedings of the National Academy of Sciences of the United States of America 2004 Mar 9;101(10):3329-35
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of STK11 (arrow) using STK11 polyclonal antibody (Cat # PAB2804).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the STK11 gene (Lane 2).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with STK11 polyclonal antibody (Cat # PAB2804) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
