PAB12979

antibody from Abnova Corporation

Targeting: STK11 LKB1, PJS

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB12979

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB12979, RRID:AB_10553180

Product name

STK11 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of STK11.

Storage

Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade.

Hawley SA, Boudeau J, Reid JL, Mustard KJ, Udd L, Mäkelä TP, Alessi DR, Hardie DG
Journal of biology 2003;2(4):28

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MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm.

Boudeau J, Baas AF, Deak M, Morrice NA, Kieloch A, Schutkowski M, Prescott AR, Clevers HC, Alessi DR
The EMBO journal 2003 Oct 1;22(19):5102-14

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A serine/threonine kinase gene defective in Peutz-Jeghers syndrome.

Hemminki A, Markie D, Tomlinson I, Avizienyte E, Roth S, Loukola A, Bignell G, Warren W, Aminoff M, Höglund P, Järvinen H, Kristo P, Pelin K, Ridanpää M, Salovaara R, Toro T, Bodmer W, Olschwang S, Olsen AS, Stratton MR, de la Chapelle A, Aaltonen LA
Nature 1998 Jan 8;391(6663):184-7

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of STK11 in PC-3 cell lysate with STK11 polyclonal antibody (Cat # PAB12979) at 1 ug/mL in the (A) absence or (B) presence of blocking peptide.