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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB16957 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB16957, RRID:AB_10616750
- Product name
- STK11 (phospho S428) polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of STK11.
- Storage
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.
LKB1 is the upstream kinase in the AMP-activated protein kinase cascade.
The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death.
Shaw RJ, Kosmatka M, Bardeesy N, Hurley RL, Witters LA, DePinho RA, Cantley LC
Proceedings of the National Academy of Sciences of the United States of America 2004 Mar 9;101(10):3329-35
Proceedings of the National Academy of Sciences of the United States of America 2004 Mar 9;101(10):3329-35
LKB1 is the upstream kinase in the AMP-activated protein kinase cascade.
Woods A, Johnstone SR, Dickerson K, Leiper FC, Fryer LG, Neumann D, Schlattner U, Wallimann T, Carlson M, Carling D
Current biology : CB 2003 Nov 11;13(22):2004-8
Current biology : CB 2003 Nov 11;13(22):2004-8
The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death.
Karuman P, Gozani O, Odze RD, Zhou XC, Zhu H, Shaw R, Brien TP, Bozzuto CD, Ooi D, Cantley LC, Yuan J
Molecular cell 2001 Jun;7(6):1307-19
Molecular cell 2001 Jun;7(6):1307-19
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of extracts from CV-1 cells treated with forsklin.Lane 1 : Using STK11 (phospho Ser428) polyclonal antibody (Cat # PAB16957).Lane 2 : Using the same antibody preincubated with synthesized peptide.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STK11 (phospho Ser428) polyclonal antibody (Cat # PAB16957).
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
