Antibody data
- Product number
- V2944
- Provider
- NSJ Bioreagents
- Product name
- CD84 Antibody
- Provider product page
- NSJ Bioreagents - V2944
- Antibody type
- Monoclonal
- Antigen
- Spleen cells of a patient with hairy cell leukemia were used as the immunogen for the CD84 antibody.
- Description
- Protein G purified antibody
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- 152-1D5
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the CD84 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
CD84 is a survival receptor for CLL cells.
Binsky-Ehrenreich I, Marom A, Sobotta MC, Shvidel L, Berrebi A, Hazan-Halevy I, Kay S, Aloshin A, Sagi I, Goldenberg DM, Leng L, Bucala R, Herishanu Y, Haran M, Shachar I
Oncogene 2014 Feb 20;33(8):1006-16
Missense mutations in SH2D1A identified in patients with X-linked lymphoproliferative disease differentially affect the expression and function of SAP.
Hare NJ, Ma CS, Alvaro F, Nichols KE, Tangye SG
International immunology 2006 Jul;18(7):1055-65
Functional requirements for interactions between CD84 and Src homology 2 domain-containing proteins and their contribution to human T cell activation.
Tangye SG, Nichols KE, Hare NJ, van de Weerdt BC
Journal of immunology (Baltimore, Md. : 1950) 2003 Sep 1;171(5):2485-95
CD84 is up-regulated on a major population of human memory B cells and recruits the SH2 domain containing proteins SAP and EAT-2.
Tangye SG, van de Weerdt BC, Avery DT, Hodgkin PD
European journal of immunology 2002 Jun;32(6):1640-9
Genomic characterization of CD84 reveals the existence of five isoforms differing in their cytoplasmic domains.
Palou E, Pirotto F, Solé J, Freed JH, Peral B, Vilardell C, Vilella R, Vives J, Gayá A
Tissue antigens 2000 Feb;55(2):118-27
CD84 leukocyte antigen is a new member of the Ig superfamily.
de la Fuente MA, Pizcueta P, Nadal M, Bosch J, Engel P
Blood 1997 Sep 15;90(6):2398-405
Supportive validation
- Submitted by
-
NSJ Bioreagents (provider)
- Main image
- Experimental details
- SDS-PAGE Analysis of Purified, BSA-Free CD84 Antibody (clone 152-1D5). Confirmation of Integrity and Purity of the Antibody.
Recommended by provider
Supportive data in Antibodypedia