Explore
Validate
LearnABIN359321
antibody from antibodies-online
Targeting: PANK2
C20orf48, FLJ11729, HARP, HSS, NBIA1, PKAN
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN359321 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Pantothenate Kinase 2 (PANK2) (Middle Region) antibody
- Antibody type
- Polyclonal
- Description
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- Middle Region
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references The diverse phenotype and genotype of pantothenate kinase-associated neurodegeneration.
Compound heterozygous PANK2 mutations confirm HARP and Hallervorden-Spatz syndromes are allelic.
An isoform of hPANK2, deficient in pantothenate kinase-associated neurodegeneration, localizes to mitochondria.
HARP syndrome is allelic with pantothenate kinase-associated neurodegeneration.
A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome.
Pellecchia MT, Valente EM, Cif L, Salvi S, Albanese A, Scarano V, Bonuccelli U, Bentivoglio AR, D'Amico A, Marelli C, Di Giorgio A, Coubes P, Barone P, Dallapiccola B
Neurology 2005 May 24;64(10):1810-2
Neurology 2005 May 24;64(10):1810-2
Compound heterozygous PANK2 mutations confirm HARP and Hallervorden-Spatz syndromes are allelic.
Houlden H, Lincoln S, Farrer M, Cleland PG, Hardy J, Orrell RW
Neurology 2003 Nov 25;61(10):1423-6
Neurology 2003 Nov 25;61(10):1423-6
An isoform of hPANK2, deficient in pantothenate kinase-associated neurodegeneration, localizes to mitochondria.
Hörtnagel K, Prokisch H, Meitinger T
Human molecular genetics 2003 Feb 1;12(3):321-7
Human molecular genetics 2003 Feb 1;12(3):321-7
HARP syndrome is allelic with pantothenate kinase-associated neurodegeneration.
Ching KH, Westaway SK, Gitschier J, Higgins JJ, Hayflick SJ
Neurology 2002 Jun 11;58(11):1673-4
Neurology 2002 Jun 11;58(11):1673-4
A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome.
Zhou B, Westaway SK, Levinson B, Johnson MA, Gitschier J, Hayflick SJ
Nature genetics 2001 Aug;28(4):345-9
Nature genetics 2001 Aug;28(4):345-9
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
