66563-1-Ig

antibody from Proteintech Group

Targeting: ATF6 ATF6A

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

66563-1-Ig

Provider

Proteintech Group

Product name

ATF6 antibody

Antibody type

Monoclonal

Description

ATF6 antibody (Cat. #66563-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

3B7E4

Vial size

20ul, 150ul

References

Submitted references

Endoplasmic reticulum stress is attenuated by glycolysis in lymphatic malformations.

Li X, Zhong W, Jiang H, Wang P, Chai M, Zhu T, Liu J, Huang C, Yang S, Mou D, Zhou X, Cai Y
Pediatric research 2024 Oct;96(5):1210-1219

---

Formononetin attenuates cigarette smoke-induced COPD in mice by suppressing inflammation, endoplasmic reticulum stress, and apoptosis in bronchial epithelial cells via AhR/CYP1A1 and AKT/mTOR signaling pathways.

Li X, Jiang X, Zeng R, Lai X, Wang J, Liu H, Wu H, He J, Liu L, Zhu Z, Li J, Liang X
Phytotherapy research : PTR 2024 Mar;38(3):1278-1293

---

Acetylation of mtHSP70 at Lys595/653 affecting its interaction between GrpEL1 regulates glioblastoma progression via UPRmt.

Gao B, Wang Z, Dai K, Wang Y, Li L, Li G, Niu X, Li X, Yu Z, Wang Z, Chen G
Free radical biology & medicine 2024 Mar;213:394-408

---

PP4R1 accelerates the malignant progression of NSCLC via up-regulating HSPA6 expression and HSPA6-mediated ER stress.

Zhu X, Chen X, Shen X, Liu Y, Fu W, Wang B, Zhao L, Yang F, Mo N, Zhong G, Jiang S, Yang Z
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119588

---

Ethanol-Induced Hepatic Ferroptosis Is Mediated by PERK-Dependent MAMs Formation: Preventive Role of Quercetin.

Lin H, Guo X, Liu J, Tang Y, Chen L, Chen H, Zhao Y, Wang L, Li H, Yu J, Yao P
Molecular nutrition & food research 2024 Apr;68(7):e2300343

---

CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance.

Takasugi M, Ohtani N, Takemura K, Emmrich S, Zakusilo FT, Yoshida Y, Kutsukake N, Mariani JN, Windrem MS, Chandler-Militello D, Goldman SA, Satoh J, Ito S, Seluanov A, Gorbunova V
Cell reports 2023 Sep 26;42(9):113130

---

Soluble epoxide hydrolase deficiency attenuates airway inflammation in COPD via IRE1α/JNK/AP-1 signaling pathway.

Yu Y, Yang A, He X, Wu B, Wu Y, Li Y, Nie S, Xu B, Wang H, Yu G
Journal of inflammation (London, England) 2023 Nov 1;20(1):36

---

Selenoproteins synergistically protect porcine skeletal muscle from oxidative damage via relieving mitochondrial dysfunction and endoplasmic reticulum stress.

Jing J, He Y, Liu Y, Tang J, Wang L, Jia G, Liu G, Chen X, Tian G, Cai J, Che L, Kang B, Zhao H
Journal of animal science and biotechnology 2023 Jun 4;14(1):79

---

ATF6-Mediated Signaling Contributes to PARP Inhibitor Resistance in Ovarian Cancer.

McMellen A, Yamamoto TM, Qamar L, Sanders BE, Nguyen LL, Ortiz Chavez D, Bapat J, Berning A, Post MD, Johnson J, Behbakht K, Nurmemmedov E, Chuong EB, Bitler BG
Molecular cancer research : MCR 2023 Jan 3;21(1):3-13

---

The UDPase ENTPD5 regulates ER stress-associated renal injury by mediating protein N-glycosylation.

Xu L, Zhou Y, Wang G, Bo L, Jin B, Dai L, Lu Q, Cai X, Hu L, Liu L, Wu Y, Chang X, Huang Y, Song L, Zhang T, Wang Y, Xiao Y, Zhang F, Liu L, Shi M, Wang T, Guo B
Cell death & disease 2023 Feb 27;14(2):166

---

The synthetic oleanane triterpenoid CDDO-2P-Im binds GRP78/BiP to induce unfolded protein response-mediated apoptosis in myeloma.

Luo G, Aldridge K, Chen T, Aslot V, Kim BG, Han EH, Singh N, Li S, Xiao TS, Sporn MB, Letterio JJ
Molecular oncology 2023 Dec;17(12):2526-2545

---

Proteome and Glycoproteome Analyses Reveal the Protein N-Linked Glycosylation Specificity of STT3A and STT3B.

Wen P, Chen J, Zuo C, Gao X, Fujita M, Yang G
Cells 2022 Sep 6;11(18)

---

Exosomal DNAJB11 promotes the development of pancreatic cancer by modulating the EGFR/MAPK pathway.

Liu P, Zu F, Chen H, Yin X, Tan X
Cellular & molecular biology letters 2022 Oct 8;27(1):87

---

Role of estrogen receptors in thyroid toxicity induced by mono (2-ethylhexyl) phthalate via endoplasmic reticulum stress: An in vitro mechanistic investigation.

Xu Q, Zhou L, Ri H, Li X, Zhang X, Qi W, Ye L
Environmental toxicology and pharmacology 2022 Nov;96:104007

---

Antigen-derived peptides engage the ER stress sensor IRE1α to curb dendritic cell cross-presentation.

Guttman O, Le Thomas A, Marsters S, Lawrence DA, Gutgesell L, Zuazo-Gaztelu I, Harnoss JM, Haag SM, Murthy A, Strasser G, Modrusan Z, Wu T, Mellman I, Ashkenazi A
The Journal of cell biology 2022 Jun 6;221(6)

---

Endoplasmic reticulum stress activates human IRE1α through reversible assembly of inactive dimers into small oligomers.

Belyy V, Zuazo-Gaztelu I, Alamban A, Ashkenazi A, Walter P
eLife 2022 Jun 22;11

---

The role of ER stress and ATP/AMPK in oxidative stress meditated hepatotoxicity induced by citrinin.

Wu J, Yang C, Yang M, Liang Z, Wu Y, Kong X, Fan H, Wang S, Ning C, Xiao W, Jin Y, Yi J, Yuan Z
Ecotoxicology and environmental safety 2022 Jun 1;237:113531

---

Benzaldehyde Attenuates the Fifth Stage Larval Excretory-Secretory Product of Angiostrongylus cantonensis-Induced Injury in Mouse Astrocytes via Regulation of Endoplasmic Reticulum Stress and Oxidative Stress.

Chen KY, Chen YJ, Cheng CJ, Jhan KY, Wang LC
Biomolecules 2022 Jan 21;12(2)

---

A missing piece of the puzzle in pulmonary fibrosis: anoikis resistance promotes fibroblast activation.

Yin J, Wang J, Zhang X, Liao Y, Luo W, Wang S, Ding J, Huang J, Chen M, Wang W, Fang S, Chao J
Cell & bioscience 2022 Feb 25;12(1):21

---

Role of endoplasmic reticulum stress in cadmium-induced hepatocyte apoptosis and the protective effect of quercetin.

Wang J, Ding L, Wang K, Huang R, Yu W, Yan B, Wang H, Zhang C, Yang Z, Liu Z
Ecotoxicology and environmental safety 2022 Aug;241:113772

---

IL-6/STAT3 Induced Neuron Apoptosis in Hypoxia by Downregulating ATF6 Expression.

Zhou S, Zhong Z, Huang P, Xiang B, Li X, Dong H, Zhang G, Wu Y, Li P
Frontiers in physiology 2021;12:729925

---

Non-canonical activation of the ER stress sensor ATF6 by Legionella pneumophila effectors.

Ibe NU, Subramanian A, Mukherjee S
Life science alliance 2021 Dec;4(12)

---

POST1/C12ORF49 regulates the SREBP pathway by promoting site-1 protease maturation.

Xiao J, Xiong Y, Yang LT, Wang JQ, Zhou ZM, Dong LW, Shi XJ, Zhao X, Luo J, Song BL
Protein & cell 2021 Apr;12(4):279-296

---

Olanzapine-Induced Activation of Hypothalamic Astrocytes and Toll-Like Receptor-4 Signaling via Endoplasmic Reticulum Stress Were Related to Olanzapine-Induced Weight Gain.

He M, Qian K, Zhang Y, Huang XF, Deng C, Zhang B, Gao G, Li J, Xie H, Sun T
Frontiers in neuroscience 2020;14:589650

---

Suhuang antitussive capsule inhibits NLRP3 inflammasome activation and ameliorates pulmonary dysfunction via suppression of endoplasmic reticulum stress in cough variant asthma.

Qin W, Wu X, Jia Y, Tong X, Guo C, Chen D, Wang Z, Tan N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109188