Antibody data

Product number
BS60231 - Provider product page
Provider
Bioworld Technology, Inc
Product name
RGS4 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human RGS4.
Description
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. In mammals, G protein Ï«, ÉÇ and ÎÛ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their Ï« subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four GÏ« GTPase-activating proteins (GAPs) have been identified and are designated RGS1 (regulator of G protein signaling), RGS4, RGS10 and GAIP (GÏ«-interacting protein). Each of these proteins has been shown to deactivate specific GÏ« isoforms by increasing the rate at which they convert GTP to GDP. RGS1, RGS4 and GAIP bind tightly to and exhibit GAP activity towards GÏ« i, GÏ« o and GÏ« t, but not GÏ« s. RGS10 increases the GTP hydrolytic activity of several members of the GÏ« i subfamily including GÏ« i-3, GÏ« z, and GÏ« o.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
RGS4 protein structure - BS60231 shown in red.