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- References [12]
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- Product number
- 15681-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15681-1-AP, RRID:AB_2130496
- Product name
- KHK antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated KHK antibody (Cat. #15681-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Maternal Fructose Intake During Pregnancy Induced the Hepatic Glucose Homeostasis Imbalance in the Offspring by Inhibiting Glucokinase.
Oxyberberine alleviates fructose-induced hyperuricemia by modulating purine metabolism and gut microbiota.
Mechanistic insights into metformin's anti-hyperuricemic effect: Targeting PPP/DNPB/XOD-mediated purine pathway, purinosome assembly, and gut microbiota homostasis in rats.
Prolonged Fructose Overconsumption Activates Original Biosynthetic and Metabolic Pathways of Endogenous Purine in Rats.
Identification of TPI1 As a potential therapeutic target in pancreatic cancer with dependency of TP53 mutation using multi-omics analysis.
NAT10/ac4C/FOXP1 Promotes Malignant Progression and Facilitates Immunosuppression by Reprogramming Glycolytic Metabolism in Cervical Cancer.
High dietary fructose promotes hepatocellular carcinoma progression by enhancing O-GlcNAcylation via microbiota-derived acetate.
Hepatic but not Intestinal FBP1 Is Required for Fructose Metabolism and Tolerance.
The small intestine shields the liver from fructose-induced steatosis.
C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis.
Ketohexokinase is involved in fructose utilization and promotes tumor progression in glioma.
Increased utilization of fructose has a positive effect on the development of breast cancer.
Miao Y, Meng Z, Chen S, Li X, Fang T, Deng X, Sun B, Chen L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Jan 31;40(2):e71426
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Jan 31;40(2):e71426
Oxyberberine alleviates fructose-induced hyperuricemia by modulating purine metabolism and gut microbiota.
Tan W, Xie X, Yu Q, Yan G, Chen H, Xie Q, Liu Y, Huang X, Chen J, Xie J, Su Z, Li Y
European journal of pharmacology 2025 Oct 15;1005:178061
European journal of pharmacology 2025 Oct 15;1005:178061
Mechanistic insights into metformin's anti-hyperuricemic effect: Targeting PPP/DNPB/XOD-mediated purine pathway, purinosome assembly, and gut microbiota homostasis in rats.
Yu Q, Liao H, Tan W, Xu L, Lin G, Ai Z, Xie Q, Liu Y, Li Y, Yang X, Su Z, Ma G, Xie J, Lai Z
Chemico-biological interactions 2025 Nov 1;421:111783
Chemico-biological interactions 2025 Nov 1;421:111783
Prolonged Fructose Overconsumption Activates Original Biosynthetic and Metabolic Pathways of Endogenous Purine in Rats.
Yu Q, Tan W, Ma X, Xu L, Lin G, Cheng J, Xie Q, Liu Y, Li Y, Xian Y, Lin Z, Chen J, Su Z, Yang X, Xie J
Molecular nutrition & food research 2025 Aug;69(16):e70122
Molecular nutrition & food research 2025 Aug;69(16):e70122
Identification of TPI1 As a potential therapeutic target in pancreatic cancer with dependency of TP53 mutation using multi-omics analysis.
Toyoda T, Miura N, Kato S, Masuda T, Ohashi R, Matsushita A, Matsuda F, Ohtsuki S, Katakura A, Honda K
Cancer science 2024 Nov;115(11):3622-3635
Cancer science 2024 Nov;115(11):3622-3635
NAT10/ac4C/FOXP1 Promotes Malignant Progression and Facilitates Immunosuppression by Reprogramming Glycolytic Metabolism in Cervical Cancer.
Chen X, Hao Y, Liu Y, Zhong S, You Y, Ao K, Chong T, Luo X, Yin M, Ye M, He H, Lu A, Chen J, Li X, Zhang J, Guo X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(32):e2302705
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(32):e2302705
High dietary fructose promotes hepatocellular carcinoma progression by enhancing O-GlcNAcylation via microbiota-derived acetate.
Zhou P, Chang WY, Gong DA, Xia J, Chen W, Huang LY, Liu R, Liu Y, Chen C, Wang K, Tang N, Huang AL
Cell metabolism 2023 Nov 7;35(11):1961-1975.e6
Cell metabolism 2023 Nov 7;35(11):1961-1975.e6
Hepatic but not Intestinal FBP1 Is Required for Fructose Metabolism and Tolerance.
Bai Q, Liu Y, Wang CM, Wang JR, Feng Y, Ma X, Yang X, Shi YN, Zhang WJ
Endocrinology 2023 Apr 17;164(6)
Endocrinology 2023 Apr 17;164(6)
The small intestine shields the liver from fructose-induced steatosis.
Jang C, Wada S, Yang S, Gosis B, Zeng X, Zhang Z, Shen Y, Lee G, Arany Z, Rabinowitz JD
Nature metabolism 2020 Jul;2(7):586-593
Nature metabolism 2020 Jul;2(7):586-593
C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis.
Allen SP, Hall B, Woof R, Francis L, Gatto N, Shaw AC, Myszczynska M, Hemingway J, Coldicott I, Willcock A, Job L, Hughes RM, Boschian C, Bayatti N, Heath PR, Bandmann O, Mortiboys H, Ferraiuolo L, Shaw PJ
Brain : a journal of neurology 2019 Dec 1;142(12):3771-3790
Brain : a journal of neurology 2019 Dec 1;142(12):3771-3790
Ketohexokinase is involved in fructose utilization and promotes tumor progression in glioma.
Gao W, Li N, Li Z, Xu J, Su C
Biochemical and biophysical research communications 2018 Sep 10;503(3):1298-1306
Biochemical and biophysical research communications 2018 Sep 10;503(3):1298-1306
Increased utilization of fructose has a positive effect on the development of breast cancer.
Fan X, Liu H, Liu M, Wang Y, Qiu L, Cui Y
PeerJ 2017;5:e3804
PeerJ 2017;5:e3804
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The KHK antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human KHK. This antibody recognizes human, mouse, rat antigen. The KHK antibody has been validated for the following applications: ELISA, WB analysis.
