RA0003

antibody from Oursmab

Targeting: ACVRL1 ACVRLK1, ALK1, HHT, HHT2, ORW2

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0003

Provider

Oursmab

Product name

Ascrinvacumab (Biosimilar Reference Antibody) (ACVRL1)

Antibody type

Monoclonal

Description

Ascrinvacumab (CAS: 1463459-96-2) is a humanized IgG2 monoclonal antibody that specifically targets the activin receptor-like kinase 1 (ALK-1), a key regulator of angiogenesis. It binds to ALK-1 with high affinity (Kd = 7 nM), effectively blocking its interaction with bone morphogenetic protein 9 (BMP9) and subsequent activation of the SMAD signaling pathway.?

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.